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AI-2E family transporter [Listeria monocytogenes].


LOCUS       WP_003721924             345 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003721924
VERSION     WP_003721924.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 345)
  AUTHORS   Khera,R., Mehdipour,A.R., Bolla,J.R., Kahnt,J., Welsch,S.,
            Ermler,U., Muenke,C., Robinson,C.V., Hummer,G., Xie,H. and
            Michel,H.
  TITLE     Cryo-EM structures of pentameric autoinducer-2 exporter from
            Escherichia coli reveal its transport mechanism
  JOURNAL   EMBO J 41 (18), e109990 (2022)
   PUBMED   35698912
REFERENCE   2  (residues 1 to 345)
  AUTHORS   Rettner,R.E. and Saier,M.H. Jr.
  TITLE     The autoinducer-2 exporter superfamily
  JOURNAL   J Mol Microbiol Biotechnol 18 (4), 195-205 (2010)
   PUBMED   20559013
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10001851
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..345
                     /product="AI-2E family transporter"
                     /GO_function="GO:0015562 - efflux transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /calculated_mol_wt=39047
     Region          11..327
                     /region_name="PerM"
                     /note="Predicted PurR-regulated permease PerM [General
                     function prediction only]; COG0628"
                     /db_xref="CDD:440393"
ORIGIN      
        1 mkelslflqn rsvrrvgvfi liafvlyllr sqmniilltf ifsylitrle nfilrrisiy
       61 rqiivlllyv liaaviifvf vkyipvladq inqlvkfgnt flttdsnndf inyivslanq
      121 fdimkyteqg vsmiltyltn vgtvlmnvfi almlslffsl gkehlvsftn qfstskigfi
      181 yeevkffgsk fvatfgkvie aqfiialvna ilttialwil gfpqlmtlsi mvfllglipv
      241 agviislvpl tiigysiggv eyifyilvvv iiihalesyv lnpklmsakt nlpvfytfii
      301 lifgehffgi wglivgipvv mffldvlgvt nqeeieqpkd tisht