MULTISPECIES: cyclic-di-AMP phosphodiesterase PdeA [Listeria].

LOCUS       WP_003721675             657 aa            linear   BCT 06-MAR-2023
ACCESSION   WP_003721675
VERSION     WP_003721675.1
KEYWORDS    RefSeq.
SOURCE      Listeria
  ORGANISM  Listeria
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae.
REFERENCE   1  (residues 1 to 657)
  AUTHORS   Kellenberger,C.A., Chen,C., Whiteley,A.T., Portnoy,D.A. and
            Hammond,M.C.
  TITLE     RNA-Based Fluorescent Biosensors for Live Cell Imaging of Second
            Messenger Cyclic di-AMP
  JOURNAL   J. Am. Chem. Soc. 137 (20), 6432-6435 (2015)
   PUBMED   25965978
REFERENCE   2  (residues 1 to 657)
  AUTHORS   Huynh,T.N., Luo,S., Pensinger,D., Sauer,J.D., Tong,L. and
            Woodward,J.J.
  TITLE     An HD-domain phosphodiesterase mediates cooperative hydrolysis of
            c-di-AMP to affect bacterial growth and virulence
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 112 (7), E747-E756 (2015)
   PUBMED   25583510
REFERENCE   3  (residues 1 to 657)
  AUTHORS   Witte,C.E., Whiteley,A.T., Burke,T.P., Sauer,J.D., Portnoy,D.A. and
            Woodward,J.J.
  TITLE     Cyclic di-AMP is critical for Listeria monocytogenes growth, cell
            wall homeostasis, and establishment of infection
  JOURNAL   MBio 4 (3), e00282-e00213 (2013)
   PUBMED   23716572
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR001113
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..657
                     /organism="Listeria"
                     /db_xref="taxon:1637"
     gene            1..657
                     /gene="pdeA"
     Protein         1..657
                     /product="cyclic-di-AMP phosphodiesterase PdeA"
                     /calculated_mol_wt=74716
     Region          1..656
                     /region_name="GdpP"
                     /note="Cyclic di-AMP phosphodiesterase GdpP, contains
                     GGDEF-like and DHH domains [Signal transduction
                     mechanisms]; COG3887"
                     /db_xref="CDD:443095"
ORIGIN      
        1 msgyfqkrml kyplygliaa tiilsvitff fswwlsalvv vggiiltvam fyfeyrlned
       61 vqlyvsnlty rikrseeeal vempmgilly dehykiewvn pfmskyfdka eligesleev
      121 gpefldvitg ndekgimsia wrdhrfdtiv krkerilyly drteyydlnk kfqanksvfa
      181 vifldnydew aqgmddrrrs alnnlvtsml tnwarehriy lkristdrfm aflteemlkr
      241 leeekfqild rirertskqn ipltlsigig ykeddliqla dlaqssldla lgrggdqvvi
      301 kqpegkvrfy ggktnpmekr trvrarvisq alqelitqsd qvfvmghryp dmdvigsslg
      361 vmriaemndr nayvvvepgk mspdvkrlmn eieeypnvik nivtpqvale niteksllvv
      421 vdthkpsmvi nkelldsatn vvvvdhhrrs eefvgspvlv yiepyassta elitelfeyq
      481 pdleqvgkie atallsgivv dtknftlrtg srtfdaasyl rslgadtilv qqflkeditt
      541 ftqrsrlves leiyhdgmai atghedeefg tviaaqaadt mlsmegvqas fvitlrpdkl
      601 igisarslgq invqvimekl gggghlsnaa tqlkdvtiae aekqlisaid aywkget