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MULTISPECIES: Bcr/CflA family multidrug efflux MFS transporter


LOCUS       WP_003159295             402 aa            linear   BCT 20-NOV-2023
            [Pseudomonas].
ACCESSION   WP_003159295
VERSION     WP_003159295.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008314.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11102
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..402
                     /product="Bcr/CflA family multidrug efflux MFS
                     transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /GO_process="GO:1990961 - xenobiotic detoxification by
                     transmembrane export across the plasma membrane [Evidence
                     IEA]"
                     /calculated_mol_wt=41702
     Region          22..387
                     /region_name="MFS_MdfA_MDR_like"
                     /note="Multidrug transporter MdfA and similar multidrug
                     resistance (MDR) transporters of the Major Facilitator
                     Superfamily; cd17320"
                     /db_xref="CDD:340878"
     Site            order(28..29,32..33,57,60..61,118,149,152..153,234,237,
                     357)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:340878"
ORIGIN      
        1 mpasasriqv gsgerrllll lsalvafgpl sidmylpslp aiaadlgasd aqvqrsisgf
       61 lvgfcvgmlf ygplsdrfgr rpvllagial ylfsslacal adsagqlvll rvlqalggga
      121 asvlaramvr dlyplgeaar mlalmhmvtm laplaapllg gylmlwagwr alfvvlalfa
      181 glcllavwrv aeshpperrg gslaqaflay grllgdrral gyvlcmglaf agmfayisaa
      241 pfvfiehfgv raerfgwffg lnilgvmlat wcsarlvrrh gprpllrags llacvsglfl
      301 lgyaalgerg glwalvpgll cfvsvtgllg anciasllal ypgqagaasa vavsgqfglg
      361 claslavgwl alpgvlpmal vmavcgvgsl lalglalhgg nr