MFS transporter [Pseudomonas aeruginosa].

LOCUS       WP_003147483             403 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_003147483
VERSION     WP_003147483.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 403)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 403)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 403)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023689
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..403
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=41837
     Region          13..369
                     /region_name="MFS_SLC46_TetA_like"
                     /note="Eukaryotic Solute carrier 46 (SLC46) family,
                     Bacterial Tetracycline resistance proteins, and similar
                     proteins of the Major Facilitator Superfamily of
                     transporters; cd17330"
                     /db_xref="CDD:340888"
     Site            order(20..21,24..25,28,63,125..126,128..130,133,153,
                     156..157,160,225,228..229,232..234,237,269,273,320..321,
                     325,329,345,348..349,352..353,356)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340888"
ORIGIN      
        1 mttpppsant ldlrplmfet fvctlavmsf valvgplark lglapwqaga avtvggiawm
       61 laarpwgias drhgrrrill gglagfalsy gslclfivla lhwtlptlfa fagivllrgl
      121 aggfyaavpa ctaalvadhv eaqrraaala glgaasaigm vigpglagll athglvlpll
      181 vtgalplval lalwrwlpre errqpnrgaa laigdrrlrr plavgfvamf svtvaqitvg
      241 ffaldrlrld sadaarvagi altavgvali laqllvrrld wppprlirfg glvaaigfaa
      301 vcfadsppll wlaffvaaag mgwvfpavsa lnanavraee qgaaagtlva vhgfglisgp
      361 llgallhqld srapyalvgl llalaafwps qptrpvetrs eap