serine/threonine protein kinase PpkA [Pseudomonas aeruginosa].

LOCUS       WP_003147051            1032 aa            linear   BCT 03-NOV-2020
ACCESSION   WP_003147051
VERSION     WP_003147051.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 1032)
  AUTHORS   Pan,J., Zha,Z., Zhang,P., Chen,R., Ye,C. and Ye,T.
  TITLE     Serine/threonine protein kinase PpkA contributes to the adaptation
            and virulence in Pseudomonas aeruginosa
  JOURNAL   Microb Pathog 113, 5-10 (2017)
   PUBMED   29038052
REFERENCE   2  (residues 1 to 1032)
  AUTHORS   Goldova,J., Ulrych,A., Hercik,K. and Branny,P.
  TITLE     A eukaryotic-type signalling system of Pseudomonas aeruginosa
            contributes to oxidative stress resistance, intracellular survival
            and virulence
  JOURNAL   BMC Genomics 12, 437 (2011)
   PUBMED   21880152
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 1032)
  AUTHORS   Hsu,F., Schwarz,S. and Mougous,J.D.
  TITLE     TagR promotes PpkA-catalysed type VI secretion activation in
            Pseudomonas aeruginosa
  JOURNAL   Mol Microbiol 72 (5), 1111-1125 (2009)
   PUBMED   19400797
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR013148
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     gene            1..1032
                     /gene="ppkA"
     Protein         1..1032
                     /product="serine/threonine protein kinase PpkA"
                     /calculated_mol_wt=109887
     Region          7..261
                     /region_name="STKc_PknB_like"
                     /note="Catalytic domain of bacterial Serine/Threonine
                     kinases, PknB and similar proteins; cd14014"
                     /db_xref="CDD:270916"
     Site            order(7,31..32,61,66,71..74,86)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:270916"
     Site            order(14..15,17..20,22,35,37,69,85..88,92,94,129,131,
                     133..134,136,146..147,150,168..171)
                     /site_type="active"
                     /db_xref="CDD:270916"
     Site            order(14..15,17..20,22,35,37,69,85..88,92,131,133..134,
                     136,146..147)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270916"
     Site            order(18,92,94,129,131,133,150,168..171)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270916"
     Site            order(146..154,164..171)
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270916"
     Region          616..797
                     /region_name="vWFA"
                     /note="Von Willebrand factor type A (vWA) domain was
                     originally found in the blood coagulation protein von
                     Willebrand factor (vWF). Typically, the vWA domain is made
                     up of approximately 200 amino acid residues folded into a
                     classic a/b para-rossmann type of...; cd00198"
                     /db_xref="CDD:238119"
     Site            order(621,705,736)
                     /site_type="other"
                     /note="metal ion-dependent adhesion site (MIDAS)"
                     /db_xref="CDD:238119"
ORIGIN      
        1 mdielpgfdi erelgegama tvylatqrsl qrkvalkvma aalaadpsfa erflregrtl
       61 arlshpntvt ihdignvgsc yymameylpn gtlkeriqqg ldpeqglayv rqvaaalgya
      121 hsqglvhrdv kpanilfrad gtavlsdfgi aksiedntqf tqvgfavgtp symspeqarg
      181 qeidgradly algvvlyeil tgklpyngkd slstalahlt eplpelpieq gryqdilrql
      241 lakdpaerfp tagaliaald rlapsaleat qirplatpqg sprasnpppa epaplppadl
      301 gglqpvsiql ppvtpsagga tppppppsqa akppsppppp lppakpragg srtpliaaaa
      361 aavllaiggg awwllgsgda psaadpaplg qtpadkpqqq tpvadaeqdg gerpllmpgk
      421 ktlfqrvltk pgaaisaeag gppragavpa fsvlyvyark qvggspwlrv gassngegdg
      481 wlpasavsdw kqslvlkfte rsgrapvmfl nsaeqverll gdtraardtl tqavdhkgdp
      541 qvvavepndr aipqdqfyll pifdskesfd adgqpaqlle vasidpggsa aapqapgqag
      601 qggasgaasd tfrtgivlvv dtsvsmqpyi drvrevidgl qrqigergdl dkvsfglvgf
      661 rnntdktpgl eyvsktlvpl qpgndaqrfa elssqvratd vsshsfneda fagimqavde
      721 mdwspyagrv vllvtdagal rkndplgrtq mneaevrqaa lrkgvkiyal hlrtpagknn
      781 hgyaeqqyrs ltadanpkia dlyipvagge vnafgntvke igtvfadlvh dagnrkpqap
      841 rfdaapsvas ksaaigyamq meflgrrdpv rapqvvtawt adrdltnpal pafqvcvlls
      901 klqlnelqqs lklivdaakr tqtspkdffq eiasasayms rdpaqlvkgs nlaqsgvlge
      961 yleglpyrsk slnmtqdlwl slsvaeqqdf ideleskirl yetfhndvan wvrfgdadag
     1021 dalyrvplst lp