sensor domain-containing diguanylate cyclase [Pseudomonas

LOCUS       WP_003121736             376 aa            linear   BCT 17-NOV-2023
            aeruginosa].
ACCESSION   WP_003121736
VERSION     WP_003121736.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 376)
  AUTHORS   Hefti,M.H., Francoijs,K.J., de Vries,S.C., Dixon,R. and Vervoort,J.
  TITLE     The PAS fold. A redefinition of the PAS domain based upon
            structural prediction
  JOURNAL   Eur J Biochem 271 (6), 1198-1208 (2004)
   PUBMED   15009198
REFERENCE   2  (residues 1 to 376)
  AUTHORS   Pei,J. and Grishin,N.V.
  TITLE     GGDEF domain is homologous to adenylyl cyclase
  JOURNAL   Proteins 42 (2), 210-216 (2001)
   PUBMED   11119645
REFERENCE   3  (residues 1 to 376)
  AUTHORS   Ponting,C.P. and Aravind,L.
  TITLE     PAS: a multifunctional domain family comes to light
  JOURNAL   Curr Biol 7 (11), R674-R677 (1997)
   PUBMED   9382818
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13295427
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..376
                     /product="sensor domain-containing diguanylate cyclase"
                     /EC_number="2.7.7.65"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /calculated_mol_wt=43895
     Region          74..164
                     /region_name="PAS_3"
                     /note="PAS fold; pfam08447"
                     /db_xref="CDD:430001"
     Site            order(75,79,87,102..105,132,137)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:238075"
     Site            order(99,103,111,114..115,145,147)
                     /site_type="other"
                     /note="heme pocket [chemical binding]"
                     /db_xref="CDD:238075"
     Region          158..375
                     /region_name="GGDEF"
                     /note="GGDEF domain, diguanylate cyclase (c-di-GMP
                     synthetase) or its enzymatically inactive variants [Signal
                     transduction mechanisms]; COG2199"
                     /db_xref="CDD:441801"
ORIGIN      
        1 mrrlrfprkr idclpfgrgh wpverardcr kmderaskpp gllplsredl ektlryalei
       61 vsdgiwdwni atnqvsrsag wylmlgypph slpesvetwk siihpedypr vmasfqayld
      121 gespeyceey rcrtysgdyl wisdrgrfve fdergeprrm igahheihqr klvelelqqr
      181 neelfdwnlr leelvaerte alhrvnqala skmaeaqrls eidpltelyn rrkfeqclhh
      241 ewmrrqrhgr atalvmidvd hfkrindlfg hstgdrvlva fgrlvaselr evdvlarwgg
      301 eefilllpet gleaaaalae rlrqrvrsqs femgerltas fgvgvlndge tldlllcrvd
      361 dalyrakqrr dcvacc