MULTISPECIES: NAD-dependent epimerase/dehydratase family protein

LOCUS       WP_003121034             341 aa            linear   BCT 26-FEB-2025
            [Pseudomonas].
ACCESSION   WP_003121034
VERSION     WP_003121034.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 341)
  AUTHORS   Thoden,J.B., Hegeman,A.D., Wesenberg,G., Chapeau,M.C., Frey,P.A.
            and Holden,H.M.
  TITLE     Structural analysis of UDP-sugar binding to UDP-galactose
            4-epimerase from Escherichia coli
  JOURNAL   Biochemistry 36 (21), 6294-6304 (1997)
   PUBMED   9174344
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF013530.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF01370.27
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..341
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /calculated_mol_wt=37133
     Region          17..333
                     /region_name="Rossmann-fold NAD(P)(+)-binding proteins"
                     /note="A large family of proteins that share a
                     Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The
                     NADB domain is found in numerous dehydrogenases of
                     metabolic pathways such as glycolysis, and many other
                     redox enzymes. NAD binding involves numerous...; cl21454"
                     /db_xref="CDD:473865"
     Site            order(19,21..22,24,43..45,83..85,123..125,154,158,
                     180..183)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:187539"
     Site            order(101,125,154,158)
                     /site_type="active"
                     /db_xref="CDD:187539"
ORIGIN      
        1 mdeqplsrpg ahvkyavlga tgllghhaar airaaghdlv lihrpssqiq rlaylepecr
       61 vaemldhagl eralrgldgv ifsagyypsr prrwqeevas algqtnpfya aclqarvpri
      121 lyvgsayamp rhpqglpghe glfydslpsg kssyvlckwa ldeqareqar nglpvvigip
      181 gmvlgeldig pttgrvitai gngemthyva gqrnvidaae agrgllmale rgrigeryll
      241 tghnlemadl trriaellgq papqpmsmam aralatlgrl ryrvsgqlpl ldetaievma
      301 ggqfldgrka reelgffstt alddtllrai dwfrdngyfn a