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MULTISPECIES: tryptophan 2,3-dioxygenase [Pseudomonas].


LOCUS       WP_003120044             288 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003120044
VERSION     WP_003120044.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 288)
  AUTHORS   Matthijs,S., Baysse,C., Koedam,N., Tehrani,K.A., Verheyden,L.,
            Budzikiewicz,H., Schafer,M., Hoorelbeke,B., Meyer,J.M., De Greve,H.
            and Cornelis,P.
  TITLE     The Pseudomonas siderophore quinolobactin is synthesized from
            xanthurenic acid, an intermediate of the kynurenine pathway
  JOURNAL   Mol. Microbiol. 52 (2), 371-384 (2004)
   PUBMED   15066027
REFERENCE   2  (residues 1 to 288)
  AUTHORS   Kurnasov,O., Jablonski,L., Polanuyer,B., Dorrestein,P., Begley,T.
            and Osterman,A.
  TITLE     Aerobic tryptophan degradation pathway in bacteria: novel
            kynurenine formamidase
  JOURNAL   FEMS Microbiol. Lett. 227 (2), 219-227 (2003)
   PUBMED   14592712
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR03036.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..288
                     /gene="kynA"
     Protein         1..288
                     /product="tryptophan 2,3-dioxygenase"
                     /EC_number="1.13.11.11"
                     /GO_function="GO:0004833 - tryptophan 2,3-dioxygenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019441 - tryptophan catabolic process to
                     kynurenine [Evidence IEA]"
                     /calculated_mol_wt=32801
     Region          17..288
                     /region_name="TDO2"
                     /note="Tryptophan 2,3-dioxygenase (vermilion) [Amino acid
                     transport and metabolism]; COG3483"
                     /db_xref="CDD:442706"
ORIGIN      
        1 mcpcphsqaq getdgeaewh naaldftham sygdylkldk vldaqfplsp dhnemlfiiq
       61 hqtselwmkl mlhelraare hvksgklgpa lkmlarvsri fdqlvhawav latmtpteyn
      121 tirpylgqss gfqsyqyrei efilgnknat llkphahrae llaaleqalh tpslydeair
      181 lmaaqglpvs qerlardaaa gtcyeasvea awrqvyqape rywdlyqlae klidledsfr
      241 qwrfrhvttv eriigfkpgt ggtegvgylr smldtilfpe lwrlrsnl