LysR family transcriptional regulator [Pseudomonas aeruginosa].

LOCUS       WP_003119870             339 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003119870
VERSION     WP_003119870.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 339)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 339)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444056
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..339
                     /product="LysR family transcriptional regulator"
                     /GO_component="GO:0032993 - protein-DNA complex [Evidence
                     IEA]"
                     /GO_function="GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=37149
     Region          29..86
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          116..318
                     /region_name="PBP2_CrgA_like"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulator CrgA and its related
                     homologs, contains the type 2 periplasmic binding domain;
                     cd08422"
                     /db_xref="CDD:176114"
     Site            order(126,130,172,186,188,251,268,298)
                     /site_type="active"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176114"
     Site            order(127..128,132..133,135..136,139,143,145..151,215,
                     245..249,256..257,260)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:176114"
ORIGIN      
        1 magwethkka qwlcqlrkgm smlpdtlseq fvlyldvldg gsfsaaarkh pltpsavarr
       61 mdaleravgs tllvrtthav ratpaglafa drarrivtel rlaraeavsl stapqgliri
      121 dapvpfgrrh lapavadflk anpgldvqlr ligsfidlqg ehlgevdlvl ragplpdsrl
      181 vatslapmvr vvcaspeylr ehgvpaspge lpehagidwd nlsppyawrf qhdgklqhlr
      241 pkrarlatnn aeamvdaala glgiahlptw lcseyllrge lqalfcddgl paaeptciya
      301 lrlereassr trlllaflre rfgfpppwdq alqqrlger