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MULTISPECIES: LysR family transcriptional regulator [Pseudomonas].


LOCUS       WP_003118849             308 aa            linear   BCT 19-FEB-2025
ACCESSION   WP_003118849
VERSION     WP_003118849.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 308)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 308)
  AUTHORS   Felder,C.B., Graul,R.C., Lee,A.Y., Merkle,H.P. and Sadee,W.
  TITLE     The Venus flytrap of periplasmic binding proteins: an ancient
            protein module present in multiple drug receptors
  JOURNAL   AAPS PharmSci 1 (2), E2 (1999)
   PUBMED   11741199
REFERENCE   3  (residues 1 to 308)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444039
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..308
                     /product="LysR family transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /calculated_mol_wt=34144
     Region          8..67
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          96..294
                     /region_name="PBP2_PAO1_like"
                     /note="The C-terminal substrate-binding domain of putative
                     LysR-type transcriptional regulator PAO1-like, a member of
                     the type 2 periplasmic binding fold protein superfamily;
                     cd08412"
                     /db_xref="CDD:176104"
     Site            order(104,108,151,170,204,228,245)
                     /site_type="other"
                     /note="putative substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:176104"
     Site            order(106..108,111..112,114..115,128,130,138,141,216..217,
                     223..225,227..229,233..234,237..238,248,255..256)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:176104"
ORIGIN      
        1 mlpmaltlrq vryfiataef gqisqaaihl nisqsavtsa iqelegmlgv alftrtaqgm
       61 nltdsgrhfl nhaysiqrsv ddalnspqpd trvegtlkva asytvmgyfl phhlqrlaqw
      121 ypelelqlfe derasiergl ldgrydiavl ltgnltepgi aaetlfnser rlwlpsrhpl
      181 gekadlglad vagepyimlt vdeagqsalr ywqqsghrpq vilhtssvea vrsmvangsg
      241 vailsdlvyr pwslegkrie tlslvdpvps msvglawrrd teasagmraf reyfrqsfla
      301 pqqsssrr