methylenetetrahydrofolate reductase [NAD(P)H] [Pseudomonas

FASTA View on NCBI
LOCUS       WP_003118821             290 aa            linear   BCT 03-JUN-2024
            aeruginosa].
ACCESSION   WP_003118821
VERSION     WP_003118821.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 290)
  AUTHORS   Guenther,B.D., Sheppard,C.A., Tran,P., Rozen,R., Matthews,R.G. and
            Ludwig,M.L.
  TITLE     The structure and properties of methylenetetrahydrofolate reductase
            from Escherichia coli suggest how folate ameliorates human
            hyperhomocysteinemia
  JOURNAL   Nat Struct Biol 6 (4), 359-365 (1999)
   PUBMED   10201405
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00676.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     gene            1..290
                     /gene="metF"
     Protein         1..290
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=32098
     Region          8..288
                     /region_name="MetF"
                     /note="5,10-methylenetetrahydrofolate reductase [Amino
                     acid transport and metabolism]; COG0685"
                     /db_xref="CDD:440449"
ORIGIN      
        1 mvaskepims qserrfsfef fpakteaghe kllatarnla gykpdffsct ygaggstrdr
       61 tlstvlqldg evkvptaphl scvgdskael rellgryrea girrivalrg dlpsgmgmas
      121 gelryanelv dfirtetgdh fhievaaype vhpqarsfed dlanfvrkvk agassaitqy
      181 ffnadayfyf vervaklgvd ipvvpgimpi tnysklarfs dacgaelprw irkqleaygd
      241 dsrsiqafge qvisemcerl leggapglhf ytlnqadpsl aiwknlqlpr