MULTISPECIES: multidrug efflux RND transporter periplasmic adaptor

LOCUS       WP_003118819             383 aa            linear   BCT 20-NOV-2023
            subunit MexA [Pseudomonas].
ACCESSION   WP_003118819
VERSION     WP_003118819.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 383)
  AUTHORS   Akama,H., Matsuura,T., Kashiwagi,S., Yoneyama,H., Narita,S.,
            Tsukihara,T., Nakagawa,A. and Nakae,T.
  TITLE     Crystal structure of the membrane fusion protein, MexA, of the
            multidrug transporter in Pseudomonas aeruginosa
  JOURNAL   J Biol Chem 279 (25), 25939-25942 (2004)
   PUBMED   15117957
REFERENCE   2  (residues 1 to 383)
  AUTHORS   Li,X.Z., Nikaido,H. and Poole,K.
  TITLE     Role of mexA-mexB-oprM in antibiotic efflux in Pseudomonas
            aeruginosa
  JOURNAL   Antimicrob Agents Chemother 39 (9), 1948-1953 (1995)
   PUBMED   8540696
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category :: Antimicrobial Resistance Protein
            Evidence Source   :: Bacterial Antimicrobial Resistance Reference
                                 Gene Database
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..383
                     /gene="mexA"
     Protein         1..383
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit MexA"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=40839
     Region          4..378
                     /region_name="PRK15030"
                     /note="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrA"
                     /db_xref="CDD:184990"
ORIGIN      
        1 mqrtpamrvl vpallvaisa lsgcgkseap ppaqtpevgi vtleaqtvtl ntelpgrtna
       61 friaevrpqv ngiilkrlfk egsdvkagqq lyqidpatye adyqsaqanl astqeqaqry
      121 kllvadqavs kqqyadanaa ylqskaaveq arinlrytkv lspisgrigr savtegalvt
      181 ngqanamatv qqldpiyvdv tqpstallrl rrelasgqle ragdnaakvs lkledgsqyp
      241 legrlefsev svdegtgsvt iravfpnpnn ellpgmfvha qlqegvkqka ilapqqgvtr
      301 dlkgqatalv vnaqnkvelr vikadrvigd kwlvteglna gdkiiteglq fvqpgvevkt
      361 vpaknvasaq kadaapaktd skg