MULTISPECIES: tryptophan synthase subunit alpha [Pseudomonas].

LOCUS       WP_003115801             268 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003115801
VERSION     WP_003115801.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 268)
  AUTHORS   Dunn,M.F.
  TITLE     Allosteric regulation of substrate channeling and catalysis in the
            tryptophan synthase bienzyme complex
  JOURNAL   Arch Biochem Biophys 519 (2), 154-166 (2012)
   PUBMED   22310642
REFERENCE   2  (residues 1 to 268)
  AUTHORS   Hyde,C.C., Ahmed,S.A., Padlan,E.A., Miles,E.W. and Davies,D.R.
  TITLE     Three-dimensional structure of the tryptophan synthase alpha 2 beta
            2 multienzyme complex from Salmonella typhimurium
  JOURNAL   J Biol Chem 263 (33), 17857-17871 (1988)
   PUBMED   3053720
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00262.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..268
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..268
                     /gene="trpA"
     Protein         1..268
                     /product="tryptophan synthase subunit alpha"
                     /EC_number="4.2.1.20"
                     /GO_function="GO:0004834 - tryptophan synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=28357
     Region          6..266
                     /region_name="trpA"
                     /note="tryptophan synthase subunit alpha; Provisional;
                     PRK13111"
                     /db_xref="CDD:237285"
     Site            order(49,60,64,175,183..184,212..213,233..234)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:240075"
     Site            order(49,60,102,183)
                     /site_type="active"
                     /db_xref="CDD:240075"
     Site            order(49,60,102)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:240075"
     Site            order(54..57,59,62,65..66,104,107,129..130,132,135,155,
                     157..159,162)
                     /site_type="other"
                     /note="heterodimer interface [polypeptide binding]"
                     /db_xref="CDD:240075"
ORIGIN      
        1 msrlqtrfaq lkqenraalv tfvtagdpdy assleilkgl paagadviel gmpftdpmad
       61 gpaiqlanir aldggqtlar tlqmvrefrs gdsetplvlm gyfnpihhyg verfiaeake
      121 vgvdglivvd lppehnedlc hpaqaagidf irlttpttgd qrlptvlegs sgfvyyvsva
      181 gvtganaatl ehveeavarl rrhtdlpigi gfgirsaeha aavarladgv vvgsalidri
      241 akardnaqav kdvlalcgel aegvrnar