2-hydroxychromene-2-carboxylate isomerase [Pseudomonas aeruginosa].

LOCUS       WP_003115035             195 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003115035
VERSION     WP_003115035.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 195)
  AUTHORS   Thompson,L.C., Ladner,J.E., Codreanu,S.G., Harp,J., Gilliland,G.L.
            and Armstrong,R.N.
  TITLE     2-Hydroxychromene-2-carboxylic acid isomerase: a kappa class
            glutathione transferase from Pseudomonas putida
  JOURNAL   Biochemistry 46 (23), 6710-6722 (2007)
   PUBMED   17508726
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10122490
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..195
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..195
                     /product="2-hydroxychromene-2-carboxylate isomerase"
                     /EC_number="5.99.1.4"
                     /GO_function="GO:0018845 - 2-hydroxychromene-2-carboxylate
                     isomerase activity [Evidence IEA]"
                     /GO_function="GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /GO_process="GO:1901170 - naphthalene catabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=21343
     Region          5..194
                     /region_name="DsbA_HCCA_Iso"
                     /note="DsbA family, 2-hydroxychromene-2-carboxylate (HCCA)
                     isomerase subfamily; HCCA isomerase is a glutathione (GSH)
                     dependent enzyme involved in the naphthalene catabolic
                     pathway. It converts HCCA, a hemiketal formed
                     spontaneously after ring cleavage of 1; cd03022"
                     /db_xref="CDD:239320"
     Site            13
                     /site_type="active"
                     /note="putative catalytic residue [active]"
                     /db_xref="CDD:239320"
ORIGIN      
        1 mskqiefffd fgspttylaw tqlpriaaah gasiawrpml lggvfkatgn hspievpakg
       61 rytlhdlary akrygvplaf npafpintlt lmrgaqgylg gegfqpylka vfealwvrqq
      121 nlgkpevvaq vlaeagfdpd eflrlvgdeq vkeglkatte eavrrgvfga psffvgdqlf
      181 fgqdrldfva evlag