MULTISPECIES: bifunctional tetrahydrofolate synthase/dihydrofolate

FASTA View on NCBI
LOCUS       WP_003115014             429 aa            linear   BCT 20-NOV-2023
            synthase [Pseudomonas].
ACCESSION   WP_003115014
VERSION     WP_003115014.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008101.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10846
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..429
                     /gene="folC"
     Protein         1..429
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /GO_function="GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /GO_process="GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=46374
     Region          1..423
                     /region_name="FolC"
                     /note="Folylpolyglutamate synthase/Dihydropteroate
                     synthase [Coenzyme transport and metabolism]; COG0285"
                     /db_xref="CDD:440054"
ORIGIN      
        1 mtqrsladwl syleqlhpta idmglersre varrlglgrp akrvvtvtgt ngkgstcall
       61 aellreqgls vgvyssphll rynervridg ieagdaqlcd afsaveaarg eisltyfemg
      121 tlaafwlfer agldfavlev glggrldavn lidadlalit sigldhadwl gdtresvafe
      181 kagilragkp alcgdldppq plleqvaalg aplylrgrdy dlaladhgwh wrglaadgqa
      241 lalhdlpllg lpmenaalal qayallelpw qaerlaealr rtrvtgrldr rdlswngqpr
      301 qllldvghnp qaaqylaqrl raaaprgryl avfglladkd ldgvlepltg lvqdwavapl
      361 ptprsrpaae leaalilrqv passhadiaa aldaqcakat addvillfgs fysvaeglew
      421 larrtdkge