trans-3-hydroxy-L-proline dehydratase [Pseudomonas aeruginosa].

LOCUS       WP_003114965             344 aa            linear   BCT 18-NOV-2024
ACCESSION   WP_003114965
VERSION     WP_003114965.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 344)
  AUTHORS   Zhang,X., Kumar,R., Vetting,M.W., Zhao,S., Jacobson,M.P., Almo,S.C.
            and Gerlt,J.A.
  TITLE     A unique cis-3-hydroxy-l-proline dehydratase in the enolase
            superfamily
  JOURNAL   J Am Chem Soc 137 (4), 1388-1391 (2015)
   PUBMED   25608448
REFERENCE   2  (residues 1 to 344)
  AUTHORS   Goytia,M., Chamond,N., Cosson,A., Coatnoan,N., Hermant,D.,
            Berneman,A. and Minoprio,P.
  TITLE     Molecular and structural discrimination of proline racemase and
            hydroxyproline-2-epimerase from nosocomial and bacterial pathogens
  JOURNAL   PLoS One 2 (9), e885 (2007)
   PUBMED   17849014
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF047722.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..344
                     /product="trans-3-hydroxy-L-proline dehydratase"
                     /EC_number="4.2.1.77"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /GO_function="GO:0050346 - trans-L-3-hydroxyproline
                     dehydratase activity [Evidence IEA]"
                     /calculated_mol_wt=37213
     Region          9..334
                     /region_name="Pro_racemase"
                     /note="Proline racemase; pfam05544"
                     /db_xref="CDD:398923"
ORIGIN      
        1 mrsqrivhiv schaegevgd vivggvaapp gatlweqsrw iardqdlrnf vlneprggvf
       61 rhanllvpak dpraqmgwii mepadtppms gsnslcvatv lldsgilpmr epltrlllea
      121 pggliearae crdgkaerve irnvpsfadr ldawievegl gslqvdtayg gdsfviadar
      181 rlgfalrade aaelvatglk ithaaneqlg frhptnpdwd hlsfcqlaap perrdgvlga
      241 nnavvirpgk idrspcgtgc sarmavlqak gqlrvgerfv grsiigsefh chiesltelg
      301 grpailpcls grawitgihq ylldpddpwp qgyrlsdtwp gghc