penicillin acylase family protein [Pseudomonas aeruginosa].

LOCUS       WP_003114943             809 aa            linear   BCT 20-JAN-2025
ACCESSION   WP_003114943
VERSION     WP_003114943.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 809)
  AUTHORS   Mukherji,R., Varshney,N.K., Panigrahi,P., Suresh,C.G. and
            Prabhune,A.
  TITLE     A new role for penicillin acylases: degradation of acyl homoserine
            lactone quorum sensing signals by Kluyvera citrophila penicillin G
            acylase
  JOURNAL   Enzyme Microb Technol 56, 1-7 (2014)
   PUBMED   24564895
REFERENCE   2  (residues 1 to 809)
  AUTHORS   Verhaert,R.M., Riemens,A.M., van der Laan,J.M., van Duin,J. and
            Quax,W.J.
  TITLE     Molecular cloning and analysis of the gene encoding the
            thermostable penicillin G acylase from Alcaligenes faecalis
  JOURNAL   Appl Environ Microbiol 63 (9), 3412-3418 (1997)
   PUBMED   9292993
REFERENCE   3  (residues 1 to 809)
  AUTHORS   Duggleby,H.J., Tolley,S.P., Hill,C.P., Dodson,E.J., Dodson,G. and
            Moody,P.C.
  TITLE     Penicillin acylase has a single-amino-acid catalytic centre
  JOURNAL   Nature 373 (6511), 264-268 (1995)
   PUBMED   7816145
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11457167
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..809
                     /product="penicillin acylase family protein"
                     /EC_number="3.5.1.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA]"
                     /calculated_mol_wt=89580
     Region          37..799
                     /region_name="PvdQ"
                     /note="Acyl-homoserine lactone (AHL) acylase PvdQ
                     [Secondary metabolites biosynthesis, transport and
                     catabolism]; COG2366"
                     /db_xref="CDD:441933"
ORIGIN      
        1 msknaryawr lslgglllgl lacavyllav plgfkygeiq vghglehegr iawdaagvph
       61 iraqsledgy fllgyshard rlwqmefarr yaggtlsevf gaktlpmdrf artlgfrrta
      121 egiyanldap trvllqrysd ginaylelap aalplefslv rherpgpwgp vdslslhlly
      181 swtlsanlgm qlqrlalaeh ldlarinevf apypgerppa trdyaslyrs lhgtpdagkl
      241 lgqlpgsnve gigsnnwvvs asrsatgkpl landphlrlt npaafylasl kipglsltga
      301 nfagaplfvi ghnqriawgy tntgshiqda ylervdpqdp rryltpdgyr pfetrleria
      361 vrdgetvsle vrstrhgpvi sdiyeparlp qaqrdrlvia lawtgldrhd ktfpsllain
      421 raegweqfld aaanfgvppq nmvyadvegn igyvsagrvp lrgadddlhg lapspgwesr
      481 ydwvgyvpes akprslnpre gfiatanqri vppdnafdfg hdwvlpyryd rirewlggpg
      541 qrtledslel qndefssvma sllpkmleqv sdpelrasea fallqgwnhq aaadlaapli
      601 agywvraftr ellqprigtq llasgwnqrn ydgflrlild gqadlrfwcg qeqgcdlkln
      661 qslrraldel raahgsapsg wkwgeahaal aehvpfhktp lralfdlknn kggdnfsvnv
      721 grfdysdpan pfntriaatl rmvidladfd nsryalstrn sglpfdgatd lnelwargay
      781 iriaddapda tdrqlvlrps asssgeprp