TonB-dependent receptor [Pseudomonas aeruginosa].

LOCUS       WP_003114864             880 aa            linear   BCT 20-MAR-2023
ACCESSION   WP_003114864
VERSION     WP_003114864.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 880)
  AUTHORS   Ferguson,A.D. and Deisenhofer,J.
  TITLE     TonB-dependent receptors-structural perspectives
  JOURNAL   Biochim Biophys Acta 1565 (2), 318-332 (2002)
   PUBMED   12409204
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10102105
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..880
                     /product="TonB-dependent receptor"
                     /GO_function="GO:0015267 - channel activity [Evidence
                     IEA]"
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=95143
     Region          62..880
                     /region_name="ligand_gated_channel"
                     /note="TonB dependent/Ligand-Gated channels are created by
                     a monomeric 22 strand (22,24) anti-parallel beta-barrel.
                     Ligands apparently bind to the large extracellular loops.
                     The N-terminal 150-200 residues form a plug from the
                     periplasmic end of barrel; cd01347"
                     /db_xref="CDD:238657"
     Site            order(62..71,81..90,109..114,121..128,145..155,167..175)
                     /site_type="active"
                     /note="N-terminal plug [active]"
                     /db_xref="CDD:238657"
     Site            order(418,467)
                     /site_type="other"
                     /note="ligand-binding site [chemical binding]"
                     /db_xref="CDD:238657"
ORIGIN      
        1 mhrslhtdap lgaalllalq lapgsaaaae eqapvdpptv qlqrievtgs airrvdaeta
       61 vpisvlraee lrqqgvtste eligrlsgnq gvynssrsvg satggasfad lrgiganktl
      121 vllngrrlan naidgsavdl ntipfaaidr vevlrdgasa lygtdaiggv infitrksln
      181 egrfdsgyas pthdgggnqr nvsaswgfge leedrfnvfa vanydkqerl gakdrgytyn
      241 yqpgrgldys sgtafpgnws qganasnpla aggckgadli prngicrqsl wryldlvpet
      301 ektsvfsrat gkladehnvs leyfwsrsdn atqvgpgtlt glqidpgtaf ypgngitpgp
      361 ggfvldpsrp vevnwrqsvl gprlqssqnt gqrlllgfdg qfagwdydig asynqnkvvd
      421 hihsgyvddr aaalgiangt lnpfgpqtda glaylgshal sgdfrtsvgr vkgldarasr
      481 eigdwfgagp aalalggefr keafhqdiqd fagnvqslgv dpaatvsger nlkaqyaeln
      541 vpvldslels aairhdkysd fgstsnpkys frfqpfrqlv lrgaysegfr apslyelynp
      601 tfttytsany ddprlcaggq psqggianrd caqqfynatg gntdlrpeta rnvtlglvyq
      661 plrdlsvgld fwwirianqi aefpeaaifa dpqayagriv rkadgsidhv vtglanlgkv
      721 ktsgvdlsld yrfpasrygq fgldlqgtyv srydfqqqig gqyldnvgdf qgvgviarwk
      781 hvanatwsrd awqatlsnry tsgyndydra shgkvgswnl wdlagsyrls halgltlgvk
      841 nlfdreppfs nqtytfqsgy dprytdpygr ilfgrlsysf