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MULTISPECIES: MFS transporter [Pseudomonas].


LOCUS       WP_003114846             427 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_003114846
VERSION     WP_003114846.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 427)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 427)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 427)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024122
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..427
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=44823
     Region          28..410
                     /region_name="MFS_YcxA_like"
                     /note="MFS-type transporter YcxA and similar proteins of
                     the Major Facilitator Superfamily of transporters;
                     cd17355"
                     /db_xref="CDD:340913"
     Site            order(39..40,43..44,47,82,129..130,132..134,137,158,
                     161..162,165,240,243..244,247..249,252,282,286,335..336,
                     340,344,360,364..365,368..369,372)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340913"
ORIGIN      
        1 msgvareame dvapaapgvg efgvascgvl lasvvgvifg ptglvissfs lfiepiaadl
       61 dwdrgqsalp vtllglaval ssplkgwlvd rwgaralvlp ltaalalcla slalarsgwq
      121 lyllfallgl ltpgnipyar ilggwferrr gaaygilglg fgvggplaly lgsacidafg
      181 wratflvygl legllalpll yalfrerpgd lpqarrtpad alpgatpgqa wrsadfwliv
      241 gnlilgvfav tgvmvhgvpl lqerglsrev atdvlaalwv gmivsqpalg ylldrydtpr
      301 ialpfallaa lgllllllgg ppallwgavf liglgagget gttqyfvsry fglrhfsviy
      361 gsiqpftfai aislgswllg yfydragsya gstlvllgaf gvaagllvml gryryaidge
      421 arshgrd