cyclic nucleotide-binding/CBS domain-containing protein

LOCUS       WP_003114809             599 aa            linear   BCT 13-NOV-2017
            [Pseudomonas aeruginosa].
ACCESSION   WP_003114809
VERSION     WP_003114809.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11458464
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..599
                     /product="cyclic nucleotide-binding/CBS domain-containing
                     protein"
                     /calculated_mol_wt=66433
     Region          11..119
                     /region_name="CAP_ED"
                     /note="effector domain of the CAP family of transcription
                     factors; members include CAP (or cAMP receptor protein
                     (CRP)), which binds cAMP, FNR (fumarate and nitrate
                     reduction), which uses an iron-sulfur cluster to sense
                     oxygen) and CooA, a heme containing CO...; cd00038"
                     /db_xref="CDD:237999"
     Site            order(76..77,86..88)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:237999"
     Site            order(107..109,113..115)
                     /site_type="other"
                     /note="flexible hinge region"
                     /db_xref="CDD:237999"
     Region          149..263
                     /region_name="CBS_pair_CAP-ED_NT_Pol-beta-
                     like_DUF294_assoc"
                     /note="Two tandem repeats of the cystathionine
                     beta-synthase (CBS pair) domains associated with the
                     bacterial CAP_ED (cAMP receptor protein effector domain)
                     family of transcription factors, the NT
                     (Nucleotidyltransferase) Pol-beta-like domain, and the
                     DUF294 dom; cd04589"
                     /db_xref="CDD:341365"
     Site            order(150,152..154,176..178,242,254,256,258..259,262)
                     /site_type="other"
                     /note="putative ligand binding site II [chemical binding]"
                     /db_xref="CDD:341365"
     Region          150..215
                     /region_name="CBS repeat"
                     /note="CBS repeat [structural motif]"
                     /db_xref="CDD:341365"
     Site            order(176,190,194..195,198,220,242..244,258)
                     /site_type="other"
                     /note="putative ligand binding site I [chemical binding]"
                     /db_xref="CDD:341365"
     Region          220..262
                     /region_name="CBS repeat"
                     /note="CBS repeat [structural motif]"
                     /db_xref="CDD:341365"
     Region          289..421
                     /region_name="DUF294"
                     /note="Putative nucleotidyltransferase DUF294; pfam03445"
                     /db_xref="CDD:460919"
     Region          458..594
                     /region_name="DUF294_C"
                     /note="Putative nucleotidyltransferase substrate binding
                     domain; pfam10335"
                     /db_xref="CDD:463050"
ORIGIN      
        1 mpdsfnfasp pfdqlrphqr etlkqalsvg yyapgetlle agsavpglfv llkgvveerg
       61 ddgrvfaqya addlfdvrgl fsgsskhryl aieesivyel pascfhqlcg enpgfarffq
      121 adlaakrqla qrdgqnlaef iltriarehl lpaleveasl slgdaarlql shgadallvr
      181 lerdgpelgi vtrtdlmsah frdgrselea igplahgpla svelgdflfd amilmtrqri
      241 ervavtedgq vigllhltqv lslfsthshv lalriaradd lgdlrrcaet ldtliatlag
      301 ngirlrfimq lvsalneqll erlfelllpp tlrgrccllv mgsegrgeql lktdqdnalv
      361 laddlpqeqa lammqrfsaa llefgyppcp ggvmasrpew ckplaawqae lrgtllegkp
      421 eqllrlsila dawpvagnlq lfeplrwqlr gfadggerwl adiaaaalqf dtpltflgql
      481 ktqdarldlk rggifpivhg irtlalregl etrgtlarie alkrhkvlea rladdlsesf
      541 elflqlrltr qlagqrdgrq qgldvsgmsr hdrdmlrygl hvvkkfkqsv arqfhletr