two-component system sensor histidine kinase/response regulator

LOCUS       WP_003114768             786 aa            linear   BCT 04-OCT-2020
            SagS [Pseudomonas aeruginosa].
ACCESSION   WP_003114768
VERSION     WP_003114768.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 786)
  AUTHORS   Dingemans,J., Al-Feghali,R.E., Lau,G.W. and Sauer,K.
  TITLE     Controlling chronic Pseudomonas aeruginosa infections by
            strategically interfering with the sensory function of SagS
  JOURNAL   Mol. Microbiol. 111 (5), 1211-1228 (2019)
   PUBMED   30710463
REFERENCE   2  (residues 1 to 786)
  AUTHORS   Dingemans,J., Poudyal,B., Sondermann,H. and Sauer,K.
  TITLE     The Yin and Yang of SagS: Distinct Residues in the HmsP Domain of
            SagS Independently Regulate Biofilm Formation and Biofilm Drug
            Tolerance
  JOURNAL   mSphere 3 (3), e00192-18 (2018)
   PUBMED   29848761
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 786)
  AUTHORS   Petrova,O.E. and Sauer,K.
  TITLE     SagS contributes to the motile-sessile switch and acts in concert
            with BfiSR to enable Pseudomonas aeruginosa biofilm formation
  JOURNAL   J. Bacteriol. 193 (23), 6614-6628 (2011)
   PUBMED   21949078
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            involved in regulating genes involved in biofilm formation.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR012801
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..786
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     gene            1..786
                     /gene="sagS"
     Protein         1..786
                     /product="two-component system sensor histidine
                     kinase/response regulator SagS"
                     /calculated_mol_wt=85730
     Region          29..>241
                     /region_name="PRK11829"
                     /note="biofilm formation regulator HmsP; Provisional"
                     /db_xref="CDD:183329"
     Region          <260..783
                     /region_name="PRK11107"
                     /note="hybrid sensory histidine kinase BarA; Provisional"
                     /db_xref="CDD:236848"
ORIGIN      
        1 mlggrtsprl ipapmdialt hrlsfkqasl tvlvafilgt llsliqvgvd yasqdasinr
       61 evralldvsh npaariayni daelaqelvl gllrspavvr aeiidtsglp lasasrepae
      121 srlrplsdfl fghkrvyedp lhvdhapgea lgvlhleidt fvfgndflrr agitllsgfv
      181 rslllslill vlfytlltkp lvsliqalsg hdprsparmr lpcpkgherd eigvlvevin
      241 rqlgrisvei eqrreaenrl tqyleelesi vaartaelka anarltlsnq eleearqtal
      301 dmaqarasfl anmsheirtp lngllgmlsl sldgpltpeq rqqlsiahds gkvlvellnd
      361 vldlskfeag qlvleqipfd lgvlvedtas llsqnaaagv eltclvdpal paqvsgdptr
      421 irqivsnlls nalkftrlgr vdvrveatae gvrisvrdtg igiaqealdr ifqpftqada
      481 gitrqyggtg lglaltrklc eamqgeltve stvglgslfs vglplapvsp plqalplrgr
      541 viaqcsansg laqllqtwlp rwgleykrle tddsllghsl dvlisdcpdc lmglrpsigt
      601 pillvtaygs flepelarrl splrqlarpl srnqlyqalk hvlehtaiap ssasdttgeq
      661 rntrvllved npvnqlvakg llhklgcqvw iaehglnalk mleehpidlv lmdcnmpvmd
      721 gyeatrqird sgrwgglpii altanalpde rercraagmd dylakpfhrd elkaildrwc
      781 pltasd