MULTISPECIES: sensor domain-containing diguanylate cyclase

LOCUS       WP_003114745             525 aa            linear   BCT 23-DEC-2024
            [Pseudomonas].
ACCESSION   WP_003114745
VERSION     WP_003114745.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 525)
  AUTHORS   Simm,R., Fetherston,J.D., Kader,A., Romling,U. and Perry,R.D.
  TITLE     Phenotypic convergence mediated by GGDEF-domain-containing proteins
  JOURNAL   J Bacteriol 187 (19), 6816-6823 (2005)
   PUBMED   16166544
  REMARK    Erratum:[J Bacteriol. 2006 Mar;188(5):2024]
REFERENCE   2  (residues 1 to 525)
  AUTHORS   Aravind,L. and Ponting,C.P.
  TITLE     The GAF domain: an evolutionary link between diverse
            phototransducing proteins
  JOURNAL   Trends Biochem Sci 22 (12), 458-459 (1997)
   PUBMED   9433123
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13413304
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..525
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..525
                     /product="sensor domain-containing diguanylate cyclase"
                     /EC_number="2.7.7.65"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /calculated_mol_wt=58199
     Region          112..>519
                     /region_name="COG5001"
                     /note="Cyclic di-GMP metabolism protein, combines GGDEF
                     and EAL domains with a 6TM membrane domain [Signal
                     transduction mechanisms]"
                     /db_xref="CDD:444025"
     Region          363..519
                     /region_name="GGDEF"
                     /note="Diguanylate-cyclase (DGC) or GGDEF domain; cd01949"
                     /db_xref="CDD:143635"
     Site            order(399,442)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:143635"
     Site            order(404,407..408,412,416,438,440..443)
                     /site_type="active"
                     /db_xref="CDD:143635"
     Site            order(434,462)
                     /site_type="active"
                     /note="I-site [active]"
                     /db_xref="CDD:143635"
ORIGIN      
        1 mtvplldptk lrrqrqimgl llglvllmal iagaalwlav rqaqqlaqpn lhnelwqtys
       61 lraeldrtld aarhtesgeg qaddlairle vlasliaplr rqslfrhlae prpevqatlq
      121 rlielsdrws dqapwgdpva arrlaaeivq qvppllepth qivvasnial tnqldvdrkr
      181 lhrafyalfw allgigagga llvlrlvadf kraqqlaghl ielnatlekr vgertrqlse
      241 gkallhfile aspsdvvlls acgasihyvs prllkrlgcq aqddfnlprl fasaseysrl
      301 qnaleargqv dgweaqlcge tpcwavicar hleidgepat liwcydisrr kameqelrll
      361 astdtltglh nrhsflhqae lmlkaaerfr hpcvalmldi dhfknindsh ghltgdralq
      421 rvaetlrqgl revdllgrlg geefaallpe vsldqaldva erlragveal rvsnpdgepl
      481 rmtvsigval rrdagddles llvradsaly qaksggrnrt eyapa