heavy metal translocating P-type ATPase [Pseudomonas aeruginosa].

LOCUS       WP_003114668             811 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_003114668
VERSION     WP_003114668.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 811)
  AUTHORS   Bublitz,M., Morth,J.P. and Nissen,P.
  TITLE     P-type ATPases at a glance
  JOURNAL   J Cell Sci 124 (Pt 15), 2515-2519 (2011)
   PUBMED   21768325
  REMARK    Erratum:[J Cell Sci. 2011 Nov 15;124(Pt 22):3917]
REFERENCE   2  (residues 1 to 811)
  AUTHORS   Chan,H., Babayan,V., Blyumin,E., Gandhi,C., Hak,K., Harake,D.,
            Kumar,K., Lee,P., Li,T.T., Liu,H.Y., Lo,T.C., Meyer,C.J.,
            Stanford,S., Zamora,K.S. and Saier,M.H. Jr.
  TITLE     The p-type ATPase superfamily
  JOURNAL   J Mol Microbiol Biotechnol 19 (1-2), 5-104 (2010)
   PUBMED   20962537
REFERENCE   3  (residues 1 to 811)
  AUTHORS   Arguello,J.M., Eren,E. and Gonzalez-Guerrero,M.
  TITLE     The structure and function of heavy metal transport P1B-ATPases
  JOURNAL   Biometals 20 (3-4), 233-248 (2007)
   PUBMED   17219055
REFERENCE   4  (residues 1 to 811)
  AUTHORS   Apell,H.J.
  TITLE     How do P-type ATPases transport ions?
  JOURNAL   Bioelectrochemistry 63 (1-2), 149-156 (2004)
   PUBMED   15110265
REFERENCE   5  (residues 1 to 811)
  AUTHORS   Axelsen,K.B. and Palmgren,M.G.
  TITLE     Evolution of substrate specificities in the P-type ATPase
            superfamily
  JOURNAL   J Mol Evol 46 (1), 84-101 (1998)
   PUBMED   9419228
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 12114434
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..811
                     /product="heavy metal translocating P-type ATPase"
                     /EC_number="7.2.2.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0019829 - ATPase-coupled monoatomic
                     cation transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0140358 - P-type transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /calculated_mol_wt=87090
     Region          6..90
                     /region_name="ATPase-cat_bd"
                     /note="Putative metal-binding domain of cation transport
                     ATPase; pfam12156"
                     /db_xref="CDD:463475"
     Region          93..798
                     /region_name="ZntA"
                     /note="Cation-transporting P-type ATPase [Inorganic ion
                     transport and metabolism]; COG2217"
                     /db_xref="CDD:441819"
ORIGIN      
        1 msaplpcyhc glpvpagsrf earvlgetra mccpgcqava eaivaggles yyrhrsenaa
       61 npealpkals eelqlydrpd vqggfvrheg elaetslmie giscaacgwl iekhlrqlpg
      121 vaearlnlsn hrlhvrwqds qlplsqllge lrqigyaghp yqpdraterl amenrralrq
      181 lgvagllwiq vmmavmatwp efnldlsagm drilrwvsli lttpivfycc gqffrgalrd
      241 lrtrhltmdv svslaiggay vagiwstitg qgelyfdavg mfalfllagr ylerrarert
      301 aastaqlvnl lpasclrlda anqgerills elrvgdrvlv ppgavlpadg vildgqssvd
      361 eslltgeylp hprqagdtvt ggtlnvegpl tvevgalgdd srlsaivrll eraqadkprl
      421 aeladkvaqw fllivllvaa avgalwwqvd hqrafwvvls llvatcpcal slatptalta
      481 atgslhklgl litrghvleg lnhidtvifd ktgtltegrl tlkqvlplrd ldadrclala
      541 aalenrsehp iarafgrape aadsvashpg lgleglvegr rlrigqaafv snlggsatpa
      601 mpgdsgqwll lgdeqgplaw fglddrlrsd apallaacka rgwrtlllsg daspmvasva
      661 aelgidearg gltpddklam lerlhgegrr vlmlgdgvnd vpvlagadis vamgsatdla
      721 ktsadavlls nrldslvqtf rlarrtrhii ienlawasly nglvlpfaal gwitpgwaai
      781 gmsvssllvv vnalrltrtp sprsvwprst s