MULTISPECIES: trpBA operon transcriptional activator TrpI

LOCUS       WP_003114633             295 aa            linear   BCT 20-NOV-2023
            [Pseudomonas].
ACCESSION   WP_003114633
VERSION     WP_003114633.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 295)
  AUTHORS   Olekhnovich,I. and Gussin,G.N.
  TITLE     Recognition of binding sites I and II by the TrpI activator protein
            of pseudomonas aeruginosa: efficient binding to both sites requires
            InGP even when site II is replaced by site I
  JOURNAL   Gene 223 (1-2), 247-255 (1998)
   PUBMED   9858743
REFERENCE   2  (residues 1 to 295)
  AUTHORS   Gao,J. and Gussin,G.N.
  TITLE     Mutations in TrpI binding site II that differentially affect
            activation of the trpBA promoter of Pseudomonas aeruginosa
  JOURNAL   EMBO J 10 (13), 4137-4144 (1991)
   PUBMED   1756720
REFERENCE   3  (residues 1 to 295)
  AUTHORS   Chang,M. and Crawford,I.P.
  TITLE     The roles of indoleglycerol phosphate and the TrpI protein in the
            expression of trpBA from Pseudomonas aeruginosa
  JOURNAL   Nucleic Acids Res 18 (4), 979-988 (1990)
   PUBMED   2107533
REFERENCE   4  (residues 1 to 295)
  AUTHORS   Chang,M., Hadero,A. and Crawford,I.P.
  TITLE     Sequence of the Pseudomonas aeruginosa trpI activator gene and
            relatedness of trpI to other procaryotic regulatory genes
  JOURNAL   J Bacteriol 171 (1), 172-183 (1989)
   PUBMED   2492495
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR014653
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..295
                     /gene="trpI"
     Protein         1..295
                     /product="trpBA operon transcriptional activator TrpI"
                     /calculated_mol_wt=32122
     Region          8..66
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          95..289
                     /region_name="PBP2_TrpI"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulator TrpI, which is
                     involved in control of tryptophan synthesis, contains type
                     2 periplasmic binding fold; cd08482"
                     /db_xref="CDD:176171"
     Site            order(95..102,104..121,123..129)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176171"
     Site            order(101..102,104,224..226,246)
                     /site_type="other"
                     /note="putative substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:176171"
ORIGIN      
        1 msrdlpslna lrafeaaarl hsislaaeel hvthgavsrq vrlleddlgv alfgkdgrgv
       61 kltdsgvrlr dacgdaferl rgvcaelrrq taeapfvlgv pgsllarwfi prldqlnral
      121 pdlrlqlsts egefdprrpg ldamlwfaep pwpadmqvfe lapermgpvv sprlaqetgl
      181 aqapaarllq epllhtasrp qawpawaasq glaaealryg qgfehlyyll eaavaglgva
      241 iapeplvrdd laagrlaapw gfietdarla lwvparlhdp ragrlaqwlr eqlag