MFS transporter [Pseudomonas aeruginosa].

LOCUS       WP_003114618             383 aa            linear   BCT 23-DEC-2024
ACCESSION   WP_003114618
VERSION     WP_003114618.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 383)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 383)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 383)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023754
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..383
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=41962
     Region          9..360
                     /region_name="MFS_MFSD6"
                     /note="Major facilitator superfamily domain-containing
                     protein 6; cd17335"
                     /db_xref="CDD:340893"
     Site            order(17..18,21..22,25,57,108..109,111..113,116,134,
                     137..138,141,211,214..215,218..220,223,250,254,304..305,
                     309,313,334,336..337,340..341,344)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340893"
ORIGIN      
        1 mtsavpywrl ssfyffyfsl lgatapflal yfhhlgfpsp rigelvaipm lmrcvapnlw
       61 gwlgdrsgqr laivrfgavc talgfslifv shsyawlalv malhaffwha vlpqfevitl
      121 ahlrersasy srirlwgsig fictvvglga lferlsldvy patllgimlg ivlcswwvpn
      181 aqpahrepre geggflaqlr qpgvlafylc vclmqlshgp yytfltlhle slgysralig
      241 llwalgvvae vmlflamprl lqrfslrqvl aasfllaslr wlllgnlads lallvfaqtl
      301 haatfgsfha aaihfvqrsf glrqqgqgqa lyaalagtgg algalysgys wnslgpawtf
      361 aiaslaalla aaiistrlqe vra