MULTISPECIES: CynX/NimT family MFS transporter [Pseudomonas].

LOCUS       WP_003114593             424 aa            linear   BCT 24-DEC-2024
ACCESSION   WP_003114593
VERSION     WP_003114593.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 424)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 424)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 424)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   4  (residues 1 to 424)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
REFERENCE   5  (residues 1 to 424)
  AUTHORS   Law,C.J., Maloney,P.C. and Wang,D.N.
  TITLE     Ins and outs of major facilitator superfamily antiporters
  JOURNAL   Annu Rev Microbiol 62, 289-305 (2008)
   PUBMED   18537473
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023805
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..424
                     /product="CynX/NimT family MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=44407
     Region          54..413
                     /region_name="MFS_NIMT_CynX_like"
                     /note="2-nitroimidazole and cyanate transporters and
                     similar proteins of the Major Facilitator Superfamily of
                     transporters; cd17339"
                     /db_xref="CDD:340897"
     Site            order(54,57..58,61,93,142..143,145..147,150,169,172..173,
                     176,244,247..248,251..253,256,283,287,336..337,341,345,
                     362,365..366,369..370,373)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340897"
ORIGIN      
        1 mthalnarpg ahpghppeel lidaevddep vppapplrpw llllglvlva lnlrpalssl
       61 apllnqvrdd tglsaaaagl lttapvlclg lfaplaprla rrigaersvl lilfclaggi
      121 vlrslfpvfg lfagsvlaga sigiigvllp givkrdfprq agvmtgvytm alclgaalaa
      181 gatapleklf gnwelalafw slpailaaaf wlpqtrqgqh ahrqafrvig lwrdplawqv
      241 tlymglqssl ayivfgwlps ilidrgmtav eaglvlsgsv mlqlitalla pwlaarardq
      301 rlavvlvmat tlagllgfly aplqtiwgwa vllglgqggt fsialalivl rsrdahvash
      361 lsgmaqgvgy tlaamgpfmv gvvhdltggw navgyifigv aiaatlfglg agrsqyvgar
      421 sehl