MULTISPECIES: penicillin-binding protein 1A [Pseudomonas].

LOCUS       WP_003114576             822 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003114576
VERSION     WP_003114576.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 822)
  AUTHORS   Sauvage,E., Kerff,F., Terrak,M., Ayala,J.A. and Charlier,P.
  TITLE     The penicillin-binding proteins: structure and role in
            peptidoglycan biosynthesis
  JOURNAL   FEMS Microbiol Rev 32 (2), 234-258 (2008)
   PUBMED   18266856
  REMARK    Erratum:[FEMS Microbiol Rev. 2008 May;32(3):556]
REFERENCE   2  (residues 1 to 822)
  AUTHORS   Zapun,A., Contreras-Martel,C. and Vernet,T.
  TITLE     Penicillin-binding proteins and beta-lactam resistance
  JOURNAL   FEMS Microbiol Rev 32 (2), 361-385 (2008)
   PUBMED   18248419
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11472030
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..822
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..822
                     /product="penicillin-binding protein 1A"
                     /EC_number="2.4.99.28"
                     /EC_number="3.4.16.4"
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /GO_function="GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=91069
     Region          1..814
                     /region_name="MrcA"
                     /note="Membrane carboxypeptidase/penicillin-binding
                     protein [Cell wall/membrane/envelope biogenesis]; COG5009"
                     /db_xref="CDD:444033"
ORIGIN      
        1 mrllkflwwt cvtlicgvll sfsgaylyls pslpsvealr nvqlqiplkv ysedgklise
       61 fgemrrtpir fadipqdfih allsaeddnf anhygvdvks lmraaaqllk sghiqtggst
      121 itmqvaknyf ltnersfsrk ineillalqi erqltkdeil elyvnkiylg nraygieaaa
      181 qvyygkpikd lslaemamia glpkapsryn plvnptrste rrnwilerml klgfidqqry
      241 qaaveepina syhvqtpeln apyiaemara emvgrygsea ytegykvitt vrsdlqnaas
      301 qsvrdglidy dqrhgyrgpe trlpgqtrda wlkhlgqqrs igglepaivt qveksgimvm
      361 trdgkeeavt wdsmkwarpf lsnnsmgpmp rqpadvaqag dqirvqrqed gtlrfvqipa
      421 aqsalisldp kdgairslvg gfsfeqsnyn raiqakrqpg ssfkpfiysa aldngftaas
      481 lvndapivfv deyldkvwrp kndtntflgp iplrealyks rnmvsirvlq glgieraisy
      541 itkfgfqrde lprnfslalg tatvtpmeia gawsvfangg ykvnpyvier iesrdgqvly
      601 qanpprvpve eqvaadaeda gnpgdpehpe saegegsiea qqvaakaqtt feptpaerii
      661 dartayimts mlqdvikrgt grralalkrt dlagktgttn dskdgwfsgy nsdyvtsvwv
      721 gfdqpetlgr reyggtvalp iwirymgfal kdkpmhtmae ppgivslrid pvtgrsaapg
      781 tpgayfemfk nedtppsvne lppgsfpgsp lpddegapid lf