pyruvate dehydrogenase (acetyl-transferring) E1 component subunit

LOCUS       WP_003114486             365 aa            linear   BCT 07-MAY-2024
            alpha [Pseudomonas aeruginosa].
ACCESSION   WP_003114486
VERSION     WP_003114486.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR03181.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     gene            1..365
                     /gene="pdhA"
     Protein         1..365
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /GO_component="GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA]"
                     /GO_process="GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /calculated_mol_wt=40284
     Region          9..351
                     /region_name="PDH_E1_alph_x"
                     /note="pyruvate dehydrogenase E1 component, alpha subunit;
                     TIGR03181"
                     /db_xref="CDD:213783"
     Site            order(90..91,132,134,162..165,192,194,261)
                     /site_type="other"
                     /note="TPP-binding site [chemical binding]"
                     /db_xref="CDD:238958"
     Site            order(112,132..133,164,166..169,172,176,180,195..198,212,
                     217,265,269)
                     /site_type="other"
                     /note="tetramer interface [polypeptide binding]"
                     /db_xref="CDD:238958"
     Site            order(127,129,131,136,139..140,143..144,146..147,150,
                     169..170,176..177,180)
                     /site_type="other"
                     /note="heterodimer interface [polypeptide binding]"
                     /db_xref="CDD:238958"
     Site            order(256..262,264..274,282..284)
                     /site_type="phosphorylation"
                     /note="phosphorylation loop region [posttranslational
                     modification]"
                     /db_xref="CDD:238958"
ORIGIN      
        1 mvhnridppf tryldsdgrp lgelpawagd sdalvglyrq mlltrlfdqk avalqrtgri
       61 gtyaptlgqe aigvaigsqm raedvlvpyy rdtavqlmrg vrmedillyw ggdergsdya
      121 eplaaqdfpi cvpiatqalh acgvasafri rgehrvavtt cgdgatskgd flealnvaga
      181 wqlpvlfvvn nnqwaisvpr riqcgaptla ekavgagfpg eqvdgndvla vaervraale
      241 rarqgkgptl lecisyrlcd httaddasry rsaeevnqaw reepikrlra flagrgqwde
      301 ereqalvgec qarvqeaver fetfaaqapq alfehvyarw pavleeqreq lleraarrrg
      361 gaehe