MULTISPECIES: nucleotide triphosphate diphosphatase NUDT15

LOCUS       WP_003114423             136 aa            linear   BCT 23-DEC-2024
            [Pseudomonas].
ACCESSION   WP_003114423
VERSION     WP_003114423.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 136)
  AUTHORS   Srouji,J.R., Xu,A., Park,A., Kirsch,J.F. and Brenner,S.E.
  TITLE     The evolution of function within the Nudix homology clan
  JOURNAL   Proteins 85 (5), 775-811 (2017)
   PUBMED   27936487
REFERENCE   2  (residues 1 to 136)
  AUTHORS   McLennan,A.G.
  TITLE     The Nudix hydrolase superfamily
  JOURNAL   Cell Mol Life Sci 63 (2), 123-143 (2006)
   PUBMED   16378245
REFERENCE   3  (residues 1 to 136)
  AUTHORS   Mildvan,A.S., Xia,Z., Azurmendi,H.F., Saraswat,V., Legler,P.M.,
            Massiah,M.A., Gabelli,S.B., Bianchet,M.A., Kang,L.W. and Amzel,L.M.
  TITLE     Structures and mechanisms of Nudix hydrolases
  JOURNAL   Arch Biochem Biophys 433 (1), 129-143 (2005)
   PUBMED   15581572
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10140375
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..136
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..136
                     /product="nucleotide triphosphate diphosphatase NUDT15"
                     /EC_number="3.6.1.9"
                     /GO_function="GO:0017110 - nucleoside diphosphate
                     phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA]"
                     /GO_process="GO:0006203 - dGTP catabolic process [Evidence
                     IEA]"
                     /GO_process="GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /GO_process="GO:0042262 - DNA protection [Evidence IEA]"
                     /calculated_mol_wt=14819
     Region          4..126
                     /region_name="NUDIX_MTH2_Nudt15"
                     /note="MutT homolog 2; cd04678"
                     /db_xref="CDD:467561"
ORIGIN      
        1 mpapqvgvgv lilrdgkvll grrkgshgag cwsapgghle fgeavedcal realeetdla
       61 lselrhgpfs ndvfegrhyl tafilagcae daearlmepd kcdgwawfdw adlpeplfap
      121 laslrrrgys pfdpkr