MFS transporter [Pseudomonas aeruginosa].

LOCUS       WP_003114382             529 aa            linear   BCT 25-MAR-2023
ACCESSION   WP_003114382
VERSION     WP_003114382.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 529)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 529)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 12067979
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..529
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=56783
     Region          6..529
                     /region_name="MFS_3"
                     /note="Transmembrane secretion effector; pfam05977"
                     /db_xref="CDD:399164"
     Site            order(27..28,31..32,35,67,122..123,125..127,130,150,
                     153..154,157,232,235..236,239..241,244,268,272,325..326,
                     330,334,350,353..354,357..358,361)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340863"
ORIGIN      
        1 mtapaaspws plrqttfrwl wlasiasnig twmhevgagw lmtslsaspl nvalvqvags
       61 lpmfflalpa galadivdkr ryllgvqlwm alvatllasl tllqltsvwl llgltlcmgi
      121 gtalmmpaws attpelvgkd elpaavalss vgvnlaravg paiagvlvsl vgpwltfaln
      181 alsffaviav llawkreavp svlpaerlfg alragwrysr ssrplqsvlv ravafflgas
      241 agmsllpliv rgelhgnamd fglllgsvgv gavlgaaflp rlrerlgsdr lvllssvlya
      301 lvlvalallr nlyllvpvml lsgaawiavl sslqvaaqts vpawvraral avyilvffgs
      361 maaggalwgl vashlsitfa llcasaalll glfaslrcrl pvteaedlap slhwpaplvd
      421 eevdqergpv mvtleydidp qdaaafqaam vevramrrrn gavswglvqd sgnrrlwlef
      481 fideswlehl rhhqrvtrge lrveaaarrf qsagvevrir hylhgaarp