MULTISPECIES: MFS transporter [Pseudomonas].

LOCUS       WP_003114355             387 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_003114355
VERSION     WP_003114355.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 387)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 387)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 387)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   4  (residues 1 to 387)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024677
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..387
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=40391
     Region          9..368
                     /region_name="MFS_YcaD_like"
                     /note="YcaD and similar transporters of the Major
                     Facilitator Superfamily; cd17477"
                     /db_xref="CDD:341030"
     Site            order(16..17,20..21,24,56,106..107,109..111,114,134,
                     137..138,141,209,212..213,216..218,221,245,249,298..299,
                     303,307,323,326..327,330..331,334)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:341030"
ORIGIN      
        1 mrwgsyfavc savisiglal gltmplvslr leswgygsfa igvmastpav gvllgamiag
       61 rlaarvgtpr lmqlclltga asvgllallq sypvwlllrl ligvqltvvf ilgeswinql
      121 avekwrgrlv alygtgyals qlsgpvlltf igtaddrgfw fgvclliags llllgrsgap
      181 rvdphsasgr glwafcrglp aiawavvlfa afeamiltll pvyglrqgfp qavalamvst
      241 vvvgdallql pigwladrvs rsglfggcgl vlllsslaip lllqtpliwp llvlfgasag
      301 glftlalili geryrddalv ranahvaqlw gigcllgpla tgaasqwisg halplmmalg
      361 aagfvvlvrl rgaipaddea tglease