lytic murein transglycosylase [Pseudomonas aeruginosa].

LOCUS       WP_003114332             448 aa            linear   BCT 19-FEB-2025
ACCESSION   WP_003114332
VERSION     WP_003114332.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 448)
  AUTHORS   Nikolaidis,I., Izore,T., Job,V., Thielens,N., Breukink,E. and
            Dessen,A.
  TITLE     Calcium-dependent complex formation between PBP2 and lytic
            transglycosylase SltB1 of Pseudomonas aeruginosa
  JOURNAL   Microb Drug Resist 18 (3), 298-305 (2012)
   PUBMED   22432706
REFERENCE   2  (residues 1 to 448)
  AUTHORS   van Asselt,E.J., Kalk,K.H. and Dijkstra,B.W.
  TITLE     Crystallographic studies of the interactions of Escherichia coli
            lytic transglycosylase Slt35 with peptidoglycan
  JOURNAL   Biochemistry 39 (8), 1924-1934 (2000)
   PUBMED   10684641
REFERENCE   3  (residues 1 to 448)
  AUTHORS   van Asselt,E.J., Thunnissen,A.M. and Dijkstra,B.W.
  TITLE     High resolution crystal structures of the Escherichia coli lytic
            transglycosylase Slt70 and its complex with a peptidoglycan
            fragment
  JOURNAL   J Mol Biol 291 (4), 877-898 (1999)
   PUBMED   10452894
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 18638440
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..448
                     /product="lytic murein transglycosylase"
                     /EC_number="4.2.2.-"
                     /GO_function="GO:0008933 - lytic transglycosylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /calculated_mol_wt=47630
     Region          56..374
                     /region_name="MltB"
                     /note="Membrane-bound lytic murein transglycosylase B
                     [Cell wall/membrane/envelope biogenesis]; COG2951"
                     /db_xref="CDD:442193"
     Region          <395..447
                     /region_name="PGRP"
                     /note="Peptidoglycan-binding (PGRP) domain of
                     peptidoglycan hydrolases [Cell wall/membrane/envelope
                     biogenesis]; COG3409"
                     /db_xref="CDD:442635"
ORIGIN      
        1 mrnpersall kvsgllgstv vamglglssa caqknptvey nqpaaplqtk apfsgagpaa
       61 svpagapnea qpgqsfeqwr dafrqqalag gidaqtfdra fagvqpdpav veadrsqpef
      121 trpvwkyleg aldplrvrqg qarlaqhari lgevdaryav dadavvaiwg mesnygshmg
      181 nknvirslat layegrrpef ahaqllaalk ilqhgdvpas fmigswagam gqtqfiptth
      241 nqyavdfdgd gkrdiwgspg dalastanyl kasgwiagqp wgfevrlpag fdyslaelti
      301 rkplgewqgm gvqgvnggpl psglsgeqas lllpaghrgp aflvlhnfra ilkynnssay
      361 alavgllads fkgggrivga wpledvplsr sqrielqrql aarghdpgav dgiigantrk
      421 airacqqefg wpadgyptpa lldrlrtp