MULTISPECIES: amino acid aminotransferase [Pseudomonas].

LOCUS       WP_003114240             399 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_003114240
VERSION     WP_003114240.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 399)
  AUTHORS   Christen,P. and Mehta,P.K.
  TITLE     From cofactor to enzymes. The molecular evolution of
            pyridoxal-5'-phosphate-dependent enzymes
  JOURNAL   Chem Rec 1 (6), 436-447 (2001)
   PUBMED   11933250
REFERENCE   2  (residues 1 to 399)
  AUTHORS   Schneider,G., Kack,H. and Lindqvist,Y.
  TITLE     The manifold of vitamin B6 dependent enzymes
  JOURNAL   Structure 8 (1), R1-R6 (2000)
   PUBMED   10673430
REFERENCE   3  (residues 1 to 399)
  AUTHORS   Mehta,P.K. and Christen,P.
  TITLE     The molecular evolution of pyridoxal-5'-phosphate-dependent enzymes
  JOURNAL   Adv Enzymol Relat Areas Mol Biol 74, 129-184 (2000)
   PUBMED   10800595
REFERENCE   4  (residues 1 to 399)
  AUTHORS   Alexander,F.W., Sandmeier,E., Mehta,P.K. and Christen,P.
  TITLE     Evolutionary relationships among pyridoxal-5'-phosphate-dependent
            enzymes. Regio-specific alpha, beta and gamma families
  JOURNAL   Eur J Biochem 219 (3), 953-960 (1994)
   PUBMED   8112347
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10013160
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..399
                     /product="amino acid aminotransferase"
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /calculated_mol_wt=43142
     Region          3..396
                     /region_name="PRK09257"
                     /note="aromatic amino acid transaminase"
                     /db_xref="CDD:181731"
     Site            order(104..106,132,184,215,244,246..247,255)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99734"
     Site            order(107,142,208,253..255,291,294)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:99734"
     Site            247
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99734"
ORIGIN      
        1 mshfakvarv pgdpilglld ayrndpradk ldlgvgvykd aqgltpilrs vklaeqrlve
       61 qettksyvgg hgdalfaarl aelalgaasp llleqradat qtpggtgalr lagdfiahcl
      121 pgrgiwlsdp twpihetlfa aaglkvshyp yvsadnrldv eamlagleri pqgdvvllha
      181 cchnptgfdl shddwrrvld vvrrrellpl idfayqgfgd gleedawavr lfagelpevl
      241 vtsscsknfg lyrdrvgali vcaqnaeklt dlrsqlafla rnlwstppah gaevvaailg
      301 dselkglwqe evegmrsria slriglveal aphglaerfa hvgaqrgmfs ytglspqqva
      361 rlrdehavyl vssgranvag ldarrldrla qaiaqvcad