ceramidase CerN [Pseudomonas aeruginosa].

LOCUS       WP_003114226             670 aa            linear   BCT 29-JUN-2021
ACCESSION   WP_003114226
VERSION     WP_003114226.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 670)
  AUTHORS   Okino,N. and Ito,M.
  TITLE     Molecular mechanism for sphingosine-induced Pseudomonas ceramidase
            expression through the transcriptional regulator SphR
  JOURNAL   Sci Rep 6, 38797 (2016)
   PUBMED   27941831
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 670)
  AUTHORS   Inoue,T., Okino,N., Kakuta,Y., Hijikata,A., Okano,H., Goda,H.M.,
            Tani,M., Sueyoshi,N., Kambayashi,K., Matsumura,H., Kai,Y. and
            Ito,M.
  TITLE     Mechanistic insights into the hydrolysis and synthesis of ceramide
            by neutral ceramidase
  JOURNAL   J Biol Chem 284 (14), 9566-9577 (2009)
   PUBMED   19088069
REFERENCE   3  (residues 1 to 670)
  AUTHORS   Okino,N., Tani,M., Imayama,S. and Ito,M.
  TITLE     Purification and characterization of a novel ceramidase from
            Pseudomonas aeruginosa
  JOURNAL   J Biol Chem 273 (23), 14368-14373 (1998)
   PUBMED   9603946
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR014470
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..670
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     gene            1..670
                     /gene="cerN"
     Protein         1..670
                     /product="ceramidase CerN"
                     /EC_number="3.5.1.23"
                     /calculated_mol_wt=73242
     Region          29..501
                     /region_name="Ceramidase_alk"
                     /note="Neutral/alkaline non-lysosomal ceramidase,
                     N-terminal; pfam04734"
                     /db_xref="CDD:461415"
     Region          503..665
                     /region_name="Ceramidse_alk_C"
                     /note="Neutral/alkaline non-lysosomal ceramidase,
                     C-terminal; pfam17048"
                     /db_xref="CDD:465340"
ORIGIN      
        1 msrsaftall lscvllalsm paraddlpyr fglgkaditg eaaevgmmgy ssleqktagi
       61 hmrqwarafv ieeaasgrrl vyvntdlgmi fqavhlkvla rlkakypgvy dennvmlaat
      121 hthsgpggfs hyamynlsvl gfqektfnai vdgivrsier aqarlqpgrl fygsgelrna
      181 nrnrsllshl knpdivgyed gidpqmsvls fvdangelag aiswfpvhst smtnanhlis
      241 pdnkgyasyh wehdvsrksg fvaafaqtna gnlspnlnlk pgsgpfdnef dntreiglrq
      301 fakayeiagq aqeevlgeld srfrfvdftr lpirpeftdg qprqlctaai gtslaagste
      361 dgpgplglee gnnpflsalg glltgvppqe lvqcqaekti ladtgnkkpy pwtptvlpiq
      421 mfrigqlell gapaeftvma gvrirravqa aseaagirhv vfngyanaya syvttreeya
      481 aqeyeggstl ygpwtqaayq qlfvdmaval rerlpvetsa iapdlsccqm nfqtgvvadd
      541 pyigksfgdv lqqpresyri gdkvtvafvt ghpkndlrte ktflevvnig kdgkqtpetv
      601 atdndwdtqy rwervgisas katiswsipp gtepghyyir hygnaknfwt qkiseiggst
      661 rsfevlgttp