tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase

LOCUS       WP_003114185             322 aa            linear   BCT 23-MAY-2024
            CmoB [Pseudomonas aeruginosa].
ACCESSION   WP_003114185
VERSION     WP_003114185.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 322)
  AUTHORS   Kim,J., Xiao,H., Bonanno,J.B., Kalyanaraman,C., Brown,S., Tang,X.,
            Al-Obaidi,N.F., Patskovsky,Y., Babbitt,P.C., Jacobson,M.P.,
            Lee,Y.S. and Almo,S.C.
  TITLE     Structure-guided discovery of the metabolite carboxy-SAM that
            modulates tRNA function
  JOURNAL   Nature 498 (7452), 123-126 (2013)
   PUBMED   23676670
REFERENCE   2  (residues 1 to 322)
  AUTHORS   Nasvall,S.J., Chen,P. and Bjork,G.R.
  TITLE     The modified wobble nucleoside uridine-5-oxyacetic acid in
            tRNAPro(cmo5UGG) promotes reading of all four proline codons in
            vivo
  JOURNAL   RNA 10 (10), 1662-1673 (2004)
   PUBMED   15383682
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00452.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     gene            1..322
                     /gene="cmoB"
     Protein         1..322
                     /product="tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic
                     acid(34) synthase CmoB"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA]"
                     /GO_process="GO:0008033 - tRNA processing [Evidence IEA]"
                     /calculated_mol_wt=36391
     Region          4..321
                     /region_name="PRK15068"
                     /note="tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic
                     acid(34) synthase CmoB"
                     /db_xref="CDD:237898"
     Site            order(128..134,151..152,178,195)
                     /site_type="other"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]"
                     /db_xref="CDD:100107"
ORIGIN      
        1 miqhlaldal qrhlagsply gwatslpaqi sarieeghgd larwwsavqr lpqvpapkvd
       61 laqrfalhsd hdaalqaqmk ealqglipwr kgpfdffgvq vdtewrsdwk wervsphvel
      121 rgkrvldvgc gngyyqwrml gagaesvvgv dpnwlflcqf laakrylpel pawhlplale
      181 dlpeklegfd tvfsmgvlyh rrspidhlla lkdclkrgge lvletlvveg dastvlvped
      241 ryaqmrnvwf lpsvaalelw lrragfadar cvdvsltsve eqrstewmrf qslpefldpq
      301 drsrtveglp apmratlvar kp