MULTISPECIES: alpha/beta hydrolase PoxA [Pseudomonas].

LOCUS       WP_003114132             292 aa            linear   BCT 22-FEB-2025
ACCESSION   WP_003114132
VERSION     WP_003114132.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 292)
  AUTHORS   Zincke,D., Balasubramanian,D., Silver,L.L. and Mathee,K.
  TITLE     Characterization of a Carbapenem-Hydrolyzing Enzyme, PoxB, in
            Pseudomonas aeruginosa PAO1
  JOURNAL   Antimicrob Agents Chemother 60 (2), 936-945 (2015)
   PUBMED   26621621
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            PoxA is encoded in strains of Pseuodmonas aeruginosa upstream of
            OXA-50 family class D beta-lactamases, which are capable of
            hydrolyzing carabapenem antibiotics.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR012764
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..292
                     /gene="poxA"
     Protein         1..292
                     /product="alpha/beta hydrolase PoxA"
                     /calculated_mol_wt=32316
     Region          13..288
                     /region_name="MenH"
                     /note="2-succinyl-6-hydroxy-2,
                     4-cyclohexadiene-1-carboxylate synthase MenH and related
                     esterases, alpha/beta hydrolase fold [Coenzyme transport
                     and metabolism, General function prediction only];
                     COG0596"
                     /db_xref="CDD:440361"
ORIGIN      
        1 mslspwfhsc sagftlrgwr sepsgkpllh flhgngfcgr tyepmlrlla edfdlwlcdi
       61 qghgesdhgg rfhgwnrnae maveafeagr gpygdvqrla cghsfggvls slvlarhptl
      121 faravlldpv lftpamigvm alsetlglql rgslakkarl rrsqwpdraa ayaglrgrgi
      181 fkgwtdealw ayveyalkes dggvelkcrp sreaeifssf prrlwpslgk ittptrvlyg
      241 drtypfvaks varwcslnpq vsahvvvggh cfmqedpada aervrdfllp np