MULTISPECIES: GDP-6-deoxy-D-mannose reductase [Pseudomonas].

LOCUS       WP_003114107             304 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003114107
VERSION     WP_003114107.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 304)
  AUTHORS   Maki,M., Jarvinen,N., Rabina,J., Roos,C., Maaheimo,H. and
            Renkonen,R.
  CONSRTM   Pirkko; Mattila
  TITLE     Functional expression of Pseudomonas aeruginosa
            GDP-4-keto-6-deoxy-D-mannose reductase which synthesizes
            GDP-rhamnose
  JOURNAL   Eur. J. Biochem. 269 (2), 593-601 (2002)
   PUBMED   11856318
REFERENCE   2  (residues 1 to 304)
  AUTHORS   Rocchetta,H.L., Pacan,J.C. and Lam,J.S.
  TITLE     Synthesis of the A-band polysaccharide sugar D-rhamnose requires
            Rmd and WbpW: identification of multiple AlgA homologues, WbpW and
            ORF488, in Pseudomonas aeruginosa
  JOURNAL   Mol. Microbiol. 29 (6), 1419-1434 (1998)
   PUBMED   9781879
  REMARK    Erratum:[Mol Microbiol 1999 Jan;31(1):397-8]
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR012627
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..304
                     /gene="rmd"
     Protein         1..304
                     /product="GDP-6-deoxy-D-mannose reductase"
                     /EC_number="1.1.1.281"
                     /calculated_mol_wt=33798
     Region          4..297
                     /region_name="Rossmann-fold NAD(P)(+)-binding proteins"
                     /note="A large family of proteins that share a
                     Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The
                     NADB domain is found in numerous dehydrogenases of
                     metabolic pathways such as glycolysis, and many other
                     redox enzymes. NAD binding involves numerous...; cl21454"
                     /db_xref="CDD:473865"
     Site            order(9,11..12,14,60..62,103..105,131,135,158..161)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:187570"
     Site            order(80,105,131,135)
                     /site_type="active"
                     /db_xref="CDD:187570"
ORIGIN      
        1 mtqrlfvtgl sgfvgkhlqa ylaaahtpwa llpvphrydl lepdslgdlw pelpdavihl
       61 agqtyvpeaf rdpartlqin llgtlnllqa lkargfsgtf lyissgdvyg qvaeaalpih
      121 eeliphprnp yavsklaaes lclqwgiteg wrvlvarpfn higpgqkdsf viasaarqia
      181 rmkqglqanr levgdidvsr dfldvqdvls aylrllshge agavynvcsg qeqkirelie
      241 lladiaqvel eivqdparmr raeqrrvrgs harlhdttgw kpeitikqsl railsdwesr
      301 vree