MULTISPECIES: beta-ketoacyl-ACP synthase FabY [Pseudomonas].

LOCUS       WP_003114068             634 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003114068
VERSION     WP_003114068.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 634)
  AUTHORS   Six,D.A., Yuan,Y., Leeds,J.A. and Meredith,T.C.
  TITLE     Deletion of the beta-acetoacetyl synthase FabY in Pseudomonas
            aeruginosa induces hypoacylation of lipopolysaccharide and
            increases antimicrobial susceptibility
  JOURNAL   Antimicrob Agents Chemother 58 (1), 153-161 (2014)
   PUBMED   24145528
REFERENCE   2  (residues 1 to 634)
  AUTHORS   Yuan,Y., Sachdeva,M., Leeds,J.A. and Meredith,T.C.
  TITLE     Fatty acid biosynthesis in Pseudomonas aeruginosa is initiated by
            the FabY class of beta-ketoacyl acyl carrier protein synthases
  JOURNAL   J Bacteriol 194 (19), 5171-5184 (2012)
   PUBMED   22753059
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR014558
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..634
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..634
                     /gene="fabY"
     Protein         1..634
                     /product="beta-ketoacyl-ACP synthase FabY"
                     /EC_number="2.3.1.180"
                     /calculated_mol_wt=68633
     Region          125..544
                     /region_name="elong_cond_enzymes"
                     /note="'elongating' condensing enzymes are a subclass of
                     decarboxylating condensing enzymes, including
                     beta-ketoacyl [ACP] synthase, type I and II and polyketide
                     synthases.They are characterized by the utlization of acyl
                     carrier protein (ACP) thioesters as...; cd00828"
                     /db_xref="CDD:238424"
     Site            order(281,434,472)
                     /site_type="active"
                     /db_xref="CDD:238424"
ORIGIN      
        1 msrlpvivgf ggynaagrss fhhgfrrmvi esmdpqarqe tlaglavmmk lvkaeggryl
       61 aedgtplspe dierryaeri fastlvrrie pqyldpdavh whkvlelspa egqaltfkas
      121 pkqlpeplpa nwsiapaedg evlvsiherc efkvdsyral tvksagqlpt gfepgelyns
      181 rfhprglqms vvaatdairs tgidwktivd nvqpdeiavf sgsimsqldd ngfgglmqsr
      241 lkghrvsakq lplgfnsmpt dfinayvlgs vgmtgsitga catflynlqk gidvitsgqa
      301 rvvivgnsea pilpeciegy samgalatee glrliegrdd vdfrrasrpf gencgftlae
      361 ssqyvvlmdd elalrlgadi hgavtdvfin adgfkksisa pgpgnyltva kavasavqiv
      421 gldtvrhasf vhahgsstpa nrvteseild rvasafgidg wpvtavkayv ghslatasad
      481 qlisalgtfk ygilpgikti dkvaddvhqq rlsisnrdmr qdkplevcfi nskgfggnna
      541 sgvvlspria ekmlrkrhgq aafaayvekr eqtraaaray dqralqgdle iiynfgqdli
      601 dehaievsae qvtvpgfsqp lvykkdarfs dmld