MULTISPECIES: iron-containing alcohol dehydrogenase [Pseudomonas].

LOCUS       WP_003114061             387 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003114061
VERSION     WP_003114061.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 387)
  AUTHORS   Shanbhag,A.P., Ghatak,A. and Rajagopal,S.
  TITLE     Industrial light at the end of the iron-containing (group III)
            alcohol dehydrogenase tunnel
  JOURNAL   Biotechnol Appl Biochem (2022) In press
   PUBMED   35751426
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (residues 1 to 387)
  AUTHORS   Carpenter,E.P., Hawkins,A.R., Frost,J.W. and Brown,K.A.
  TITLE     Structure of dehydroquinate synthase reveals an active site capable
            of multistep catalysis
  JOURNAL   Nature 394 (6690), 299-302 (1998)
   PUBMED   9685163
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10169392
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..387
                     /product="iron-containing alcohol dehydrogenase"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /calculated_mol_wt=40224
     Region          6..387
                     /region_name="HVD"
                     /note="5-hydroxyvalerate dehydrogenase (HVD) catalyzes the
                     oxidation of 5-hydroxyvalerate to 5-oxovalerate with NAD+
                     as cofactor; cd08193"
                     /db_xref="CDD:341472"
     Site            order(39,97..99,102,105,140..141,143,161..162,180,188,195,
                     199,265,269,279)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341472"
     Site            order(195,199,265,279)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:341472"
ORIGIN      
        1 mqafsfatta qilceagsai rlaelcrerr arrvlivtdp gitrlgllda ilpgfprlgl
       61 avevydqvla dppesvveaa lgrargmaae lvvgfgggss mdvaklvall ahpeagqglg
      121 evfgvgnarg prlpliqvpt tagtgsevtp iaivttgett kmgvvsphll pdlalldadl
      181 tlglppavta atgidamvha iesytsklkk nplsdllare alrllaanle ravgdggdre
      241 arqamllgac lagqafanap vaavhalayp lgghfhiphg lsnalvlpev irfnapaaag
      301 lyaelaplll gdrlrpgdrd altvqlidel aqlsprnglp srlrdagvde amlprlaada
      361 mlqqrllvnn prevgeadal aiyraay