MULTISPECIES: MFS transporter [Pseudomonas].

LOCUS       WP_003114005             392 aa            linear   BCT 28-JUL-2024
ACCESSION   WP_003114005
VERSION     WP_003114005.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 392)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 392)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023516
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..392
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=39916
     Region          12..363
                     /region_name="MFS_NepI_like"
                     /note="Purine ribonucleoside efflux pump NepI and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17324"
                     /db_xref="CDD:340882"
     Site            order(15..16,19..20,23,55,105..106,108..110,113,133,
                     136..137,140,208,211..212,215..217,220,248,252,301..302,
                     306,310,325,328..329,332..333,336)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340882"
ORIGIN      
        1 mllpilllaa agftilttef vivgllpala adlqvsvaqa gllvslfafs vaafgpflta
       61 alagverkrl fvaclllfaa analaavagd iwtmavarfv palalpvfwa masetaahla
      121 gpsregrava lvffgivaat vlgipigtli adawgwrlaf aalaalalak alllaawlpr
      181 ipgrpgislr sqasvlrqpl vlghlllsll vftgmftpyt yladilqrla gfsgslvgwt
      241 lmgfgavgll gnwlggrlvd rsplgatllf vllmalgmla lvptlgnawl laatlatwgv
      301 aqaalfivgq vrvmksapra pafaaslnis acnagigiga lagsrvidgs glaplgevga
      361 lvclaamava lllmlaprqa atepslggqi ph