bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase

LOCUS       WP_003113961             725 aa            linear   BCT 25-APR-2022
            RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL
            [Pseudomonas aeruginosa].
ACCESSION   WP_003113961
VERSION     WP_003113961.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 725)
  AUTHORS   Jiang,M., Sullivan,S.M., Walker,A.K., Strahler,J.R., Andrews,P.C.
            and Maddock,J.R.
  TITLE     Identification of novel Escherichia coli ribosome-associated
            proteins using isobaric tags and multidimensional protein
            identification techniques
  JOURNAL   J Bacteriol 189 (9), 3434-3444 (2007)
   PUBMED   17337586
REFERENCE   2  (residues 1 to 725)
  AUTHORS   Sergiev,P.V., Bogdanov,A.A. and Dontsova,O.A.
  TITLE     Ribosomal RNA guanine-(N2)-methyltransferases and their targets
  JOURNAL   Nucleic Acids Res 35 (7), 2295-2301 (2007)
   PUBMED   17389639
REFERENCE   3  (residues 1 to 725)
  AUTHORS   Lesnyak,D.V., Sergiev,P.V., Bogdanov,A.A. and Dontsova,O.A.
  TITLE     Identification of Escherichia coli m2G methyltransferases: I. the
            ycbY gene encodes a methyltransferase specific for G2445 of the 23
            S rRNA
  JOURNAL   J Mol Biol 364 (1), 20-25 (2006)
   PUBMED   17010378
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008748.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11783
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..725
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     gene            1..725
                     /gene="rlmKL"
     Protein         1..725
                     /product="bifunctional 23S rRNA
                     (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
                     (guanine(2445)-N(2))-methyltransferase RlmL"
                     /EC_number="2.1.1.173"
                     /EC_number="2.1.1.264"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0008990 - rRNA
                     (guanine-N2-)-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0031167 - rRNA methylation [Evidence IEA]"
                     /calculated_mol_wt=81025
     Region          5..723
                     /region_name="rlmL"
                     /note="bifunctional 23S rRNA
                     (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
                     (guanine(2445)-N(2))-methyltransferase RlmL; PRK11783"
                     /db_xref="CDD:236981"
ORIGIN      
        1 madvyelflt cpkgleslll eeaqglglde araqvsavrg qgslevayrl clwsrlanrv
       61 llvlarfpve naesmymavh avnwedhlda ggtlavefsg kgsgidnthf galkvkdaiv
      121 dnlrersgrr psvdkvnpdv rvhlhldrgq atlsldlsgh slhqrgyrlq qgaaplkenl
      181 aaavliragw pkiaaeggal adpmcgvgtf lveaalmaad iapnlkrerw gfsswlghvp
      241 alwrklheea qqraaaglar pplwirgyea dprliqpacn nieragvadw vkiyqgelat
      301 feprpdkgqt glvicnppyg erlgdeasll ylyqnlgerl rqscigwsag vftgapelgk
      361 rmgirshkqy afwngalack llmiqveprq fvtgergern deglarapse parlseggqm
      421 fanrlqknlr qlgkwarrdk iecyrlydad mpeyalavdi ygdwvhvqey aapksidpak
      481 aqarlfdala aipqtlgvaq ervvvkrrer qagkkqyerq ssegkflevg egdvrllvnl
      541 tdyldtglfl dhrpmrlriq keaagkrfln lfcytatatv haarggarst tsvdlsktyl
      601 dwarrnlsln gfsdkqrlvh gdvmewlred dgqyelifid pptfsnskrm egvfdvqrdh
      661 velldlamar lapggvlyfs nnfrkfelde svqaryavee itgetldpdf arnpkihraw
      721 ritvr