MULTISPECIES: O-succinylhomoserine sulfhydrylase [Pseudomonas].

LOCUS       WP_003113933             403 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003113933
VERSION     WP_003113933.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006003.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK08133
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..403
                     /product="O-succinylhomoserine sulfhydrylase"
                     /EC_number="4.2.99.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /GO_process="GO:0071268 - homocysteine biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=43054
     Region          13..402
                     /region_name="PRK08133"
                     /note="O-succinylhomoserine sulfhydrylase; Validated"
                     /db_xref="CDD:181244"
     Site            order(42..45,47..48,67,69,95..96,98..99,122,127,130,218,
                     226,228,245,254,256..257,336)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:99738"
     Site            order(96..98,122,165,194,216,218..219,228)
                     /site_type="active"
                     /note="substrate-cofactor binding pocket [active]"
                     /db_xref="CDD:99738"
     Site            order(96..98,122,194,197,216,218..219)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99738"
     Site            219
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99738"
ORIGIN      
        1 mtqdwdagrl dsdlegaafd tlavragqrr tpegehgeal fttssyvfrt aadaaarfag
       61 evpgnvysry tnptvrtfee riaalegaeq avatasgmsa ilalvmslcs sgdhvlvsrs
      121 vfgstislfd kyfkrfgiqv dypplsdlaa weaackpntk lffvespsnp laelvdiaal
      181 aeiahakgal lavdncfctp alqqplklga dvvihsatky idgqgrgmgg vvagrgeqmk
      241 evvgflrtag ptlspfnawl flkgletlri rmqahsasal alaewlerqp giervyyagl
      301 pshpqhelar rqqsgfgavv sfdvkggrda awrfidatrm vsittnlgdt kttiahpatt
      361 shgrlspedr aragigdsli rvavgledld dlkadmargl aal