MULTISPECIES: 3-hydroxyisobutyrate dehydrogenase [Pseudomonas].

LOCUS       WP_003113890             298 aa            linear   BCT 01-JUL-2024
ACCESSION   WP_003113890
VERSION     WP_003113890.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 298)
  AUTHORS   Hawes,J.W., Harper,E.T., Crabb,D.W. and Harris,R.A.
  TITLE     Structural and mechanistic similarities of 6-phosphogluconate and
            3-hydroxyisobutyrate dehydrogenases reveal a new enzyme family, the
            3-hydroxyacid dehydrogenases
  JOURNAL   FEBS Lett 389 (3), 263-267 (1996)
   PUBMED   8766712
REFERENCE   2  (residues 1 to 298)
  AUTHORS   Steele,M.I., Lorenz,D., Hatter,K., Park,A. and Sokatch,J.R.
  TITLE     Characterization of the mmsAB operon of Pseudomonas aeruginosa PAO
            encoding methylmalonate-semialdehyde dehydrogenase and
            3-hydroxyisobutyrate dehydrogenase
  JOURNAL   J Biol Chem 267 (19), 13585-13592 (1992)
   PUBMED   1339433
REFERENCE   3  (residues 1 to 298)
  AUTHORS   Rougraff,P.M., Zhang,B., Kuntz,M.J., Harris,R.A. and Crabb,D.W.
  TITLE     Cloning and sequence analysis of a cDNA for 3-hydroxyisobutyrate
            dehydrogenase. Evidence for its evolutionary relationship to other
            pyridine nucleotide-dependent dehydrogenases
  JOURNAL   J Biol Chem 264 (10), 5899-5903 (1989)
   PUBMED   2647728
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01692.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..298
                     /gene="mmsB"
     Protein         1..298
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /EC_number="1.1.1.31"
                     /GO_function="GO:0008442 - 3-hydroxyisobutyrate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0006574 - valine catabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=30355
     Region          6..295
                     /region_name="HIBADH"
                     /note="3-hydroxyisobutyrate dehydrogenase; TIGR01692"
                     /db_xref="CDD:130753"
ORIGIN      
        1 mtdiaflglg nmggpmaanl lkaghrvnvf dlqpkavlgl veqgaqgads alqccegaev
       61 vismlpagqh veslylgddg llarvagkpl lidcstiape tarkvaeaaa akgltlldap
      121 vsggvggara gtlsfivggp aegfararpv lenmgrnifh agdhgagqva kicnnmllgi
      181 lmagtaeala lgvkngldpa vlsevmkqss ggnwalnlyn pwpgvmpqap asngyaggfq
      241 vrlmnkdlgl alanaqavqa stplgalarn lfslhaqada ehegldfssi qklyrgkd