MULTISPECIES: tRNA lysidine(34) synthetase TilS [Pseudomonas].

LOCUS       WP_003113867             442 aa            linear   BCT 23-MAY-2024
ACCESSION   WP_003113867
VERSION     WP_003113867.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 442)
  AUTHORS   Soma,A., Ikeuchi,Y., Kanemasa,S., Kobayashi,K., Ogasawara,N.,
            Ote,T., Kato,J., Watanabe,K., Sekine,Y. and Suzuki,T.
  TITLE     An RNA-modifying enzyme that governs both the codon and amino acid
            specificities of isoleucine tRNA
  JOURNAL   Mol Cell 12 (3), 689-698 (2003)
   PUBMED   14527414
REFERENCE   2  (residues 1 to 442)
  AUTHORS   Zalacain,M., Biswas,S., Ingraham,K.A., Ambrad,J., Bryant,A.,
            Chalker,A.F., Iordanescu,S., Fan,J., Fan,F., Lunsford,R.D.,
            O'Dwyer,K., Palmer,L.M., So,C., Sylvester,D., Volker,C., Warren,P.,
            McDevitt,D., Brown,J.R., Holmes,D.J. and Burnham,M.K.
  TITLE     A global approach to identify novel broad-spectrum antibacterial
            targets among proteins of unknown function
  JOURNAL   J Mol Microbiol Biotechnol 6 (2), 109-126 (2003)
   PUBMED   15044829
REFERENCE   3  (residues 1 to 442)
  AUTHORS   Muramatsu,T., Yokoyama,S., Horie,N., Matsuda,A., Ueda,T.,
            Yamaizumi,Z., Kuchino,Y., Nishimura,S. and Miyazawa,T.
  TITLE     A novel lysine-substituted nucleoside in the first position of the
            anticodon of minor isoleucine tRNA from Escherichia coli
  JOURNAL   J Biol Chem 263 (19), 9261-9267 (1988)
   PUBMED   3132458
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02432.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..442
                     /gene="tilS"
     Protein         1..442
                     /product="tRNA lysidine(34) synthetase TilS"
                     /EC_number="6.3.4.19"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA]"
                     /GO_process="GO:0008033 - tRNA processing [Evidence IEA]"
                     /calculated_mol_wt=48524
     Region          25..436
                     /region_name="AANH_superfamily"
                     /note="Adenine nucleotide alpha hydrolase (AANH)
                     superfamily; cl00292"
                     /db_xref="CDD:469708"
ORIGIN      
        1 mpavplesrl lqalapwrea ggwcvafsgg ldstvllhll aqlarsealp alsalhvhhg
       61 lqaaadgwpa hcqavcrslg iplrvervqv avggsieqaa rdaryrafqa nlgegqvllt
      121 aqhlddqaet llfrllrgag lrglaampas rplgggrlcr pllgvsrael eayaqahrld
      181 wvedpsnqdp rfsrnylrre imprlashwp qavagmarca ahlreaedll aelaaidlra
      241 crqpseldwp dwldlprial eplrrlsaar qrnllrawlg qltrlpdsdh wagweslrda
      301 gddadpiwrl esgelrrgag riwwlpadwr aaagpfvwer pahplllpgn grlallgevp
      361 agplrvdyrr ggevlalagr grrdlkrlln eagvpsflrg rlpllfrade llavanipgl
      421 dspreggwrl swspptndpg ls