MULTISPECIES: M4 family elastase LasB [Pseudomonas].

FASTA View on NCBI
LOCUS       WP_003113835             498 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003113835
VERSION     WP_003113835.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 498)
  AUTHORS   Saint-Criq,V., Villeret,B., Bastaert,F., Kheir,S., Hatton,A.,
            Cazes,A., Xing,Z., Sermet-Gaudelus,I., Garcia-Verdugo,I.,
            Edelman,A. and Sallenave,J.M.
  TITLE     Pseudomonas aeruginosa LasB protease impairs innate immunity in
            mice and humans by targeting a lung epithelial cystic fibrosis
            transmembrane regulator-IL-6-antimicrobial-repair pathway
  JOURNAL   Thorax 73 (1), 49-61 (2018)
   PUBMED   28790180
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR010227
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..498
                     /gene="lasB"
     Protein         1..498
                     /product="M4 family elastase LasB"
                     /calculated_mol_wt=53556
     Region          1..496
                     /region_name="LasB"
                     /note="Zn-dependent metalloprotease (Neutral protease B)
                     [Posttranslational modification, protein turnover,
                     chaperones]; COG3227"
                     /db_xref="CDD:442460"
ORIGIN      
        1 mkkvstldll fvaimgvspa afaadlidvs klpskaaqga pgpvtlqaav gaggadelka
       61 irsttlpngk qvtryeqfhn gvrvvgeait evkgpgksva aqrsghfvan iaadlpgstt
      121 aavsaeqvla qakslkaqgr ktendkvelv irlgenniaq lvynvsylip geglsrphfv
      181 idaktgevld qweglahaea ggpggnqkig kytygsdygp livndrcemd dgnvitvdmn
      241 sstddskttp frfacptnty kqvngayspl ndahffggvv fklyrdwfgt splthklymk
      301 vhygrsvena ywdgtamlfg dgatmfyplv sldvaahevs hgfteqnsgl iyrgqsggmn
      361 eafsdmagea aefymrgknd fligydikkg sgalrymdqp srdgrsidna sqyyngidvh
      421 hssgvynraf yllanspgwd trkafevfvd anryywtats nynsgacgvi rsaqnrnysa
      481 advtrafstv gvtcpsal