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MULTISPECIES: MFS transporter [Pseudomonas].


LOCUS       WP_003113829             437 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_003113829
VERSION     WP_003113829.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 437)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 437)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 437)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024289
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..437
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=45922
     Region          20..399
                     /region_name="MFS_ShiA_like"
                     /note="Shikimate transporter and similar proteins of the
                     Major Facilitator Superfamily; cd17369"
                     /db_xref="CDD:340927"
     Site            order(32..33,36..37,40,79,137..138,140..142,145,165,
                     168..169,172,255,258..259,262..264,267,295,299,351..352,
                     356,360,376,379..380,383..384,387)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340927"
ORIGIN      
        1 mtaatlaada apepansttr vavasfigta iefydfyvya taaalvigpv ffpqtsgtaq
       61 mlsafltfgi aflarplgsa lfghfgdrig rkstlvasll lmgvsttlig vlpgydsigy
      121 waplllcvlr fgqglglgge wggaallate napagkrawf gmfpqlgpsi gflaanglfl
      181 alamllseeq frewgwripf llsaalvvvg lyvrlklaet pvfakamakh ervrlpiael
      241 faqhwrptll galamvvcya lfyistvfsl sygvaslgfs reeflgllcl avlfmaaatp
      301 lsawlsdrfg rkpvlllgsl aaiasgfame pllsqgstfs valflcielf lmgvtfapmg
      361 allpeifpth vrytgasaay nlggilgasv apyiaqklvg igglgwvggy vsaaallsll
      421 avlclketrd ndlgavs