MULTISPECIES: N-acetylglucosamine-6-phosphate deacetylase

LOCUS       WP_003113826             363 aa            linear   BCT 03-JUN-2024
            [Pseudomonas].
ACCESSION   WP_003113826
VERSION     WP_003113826.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 363)
  AUTHORS   Hall,R.S., Brown,S., Fedorov,A.A., Fedorov,E.V., Xu,C.,
            Babbitt,P.C., Almo,S.C. and Raushel,F.M.
  TITLE     Structural diversity within the mononuclear and binuclear active
            sites of N-acetyl-D-glucosamine-6-phosphate deacetylase
  JOURNAL   Biochemistry 46 (27), 7953-7962 (2007)
   PUBMED   17567048
REFERENCE   2  (residues 1 to 363)
  AUTHORS   Hall,R.S., Xiang,D.F., Xu,C. and Raushel,F.M.
  TITLE     N-Acetyl-D-glucosamine-6-phosphate deacetylase: substrate
            activation via a single divalent metal ion
  JOURNAL   Biochemistry 46 (27), 7942-7952 (2007)
   PUBMED   17567047
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00221.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..363
                     /gene="nagA"
     Protein         1..363
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /EC_number="3.5.1.25"
                     /GO_function="GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA]"
                     /GO_process="GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /calculated_mol_wt=38699
     Region          4..360
                     /region_name="NagA"
                     /note="N-acetylglucosamine-6-phosphate deacetylase, NagA,
                     catalyzes the hydrolysis of the N-acetyl group of
                     N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to
                     glucosamine 6-phosphate and acetate. This is the first
                     committed step in the biosynthetic pathway to...; cd00854"
                     /db_xref="CDD:238434"
     Site            order(50,52,120,131,183,204,207..208,238,259,292)
                     /site_type="active"
                     /db_xref="CDD:238434"
     Site            order(206,212,214..215,217,224..225,237..240,242..243,
                     245..246,249)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238434"
ORIGIN      
        1 mlegniltpq gwvlgrlhiq dgriqriege pcdpagnadp yllpgfidlh vhggggrdim
       61 eggdafatia rthrrfgtts llattmtapr eeiadilsql gaycrrsleg gsrilgvhle
      121 gpyinsgklg aqpnfahaav leevedylrr apirvitiap eiaghrplir alaergvrlq
      181 ightlgsyed gvaaleagas sfthlynamt glhhrepgiv gaalaharya elipdllhvh
      241 pgairvalrs ipclycvtds taaagmpdgq yklgshtvtk clggvrlpdg tlagstltmd
      301 qalrnlvkig lplaeasqrl sqfpadylgl aergrlapaa wadvvrldrs leldavmveg
      361 ele