Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: MFS transporter [Pseudomonas].


LOCUS       WP_003113740             435 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003113740
VERSION     WP_003113740.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 435)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 435)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 435)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022908
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..435
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=48017
     Region          11..410
                     /region_name="MFS_ExuT_GudP_like"
                     /note="Hexuronate transporter, Glucarate transporter, and
                     similar transporters of the Major Facilitator Superfamily;
                     cd17319"
                     /db_xref="CDD:340877"
     Site            order(25..26,29..30,33,66,116..117,119..121,124,144,
                     147..148,151,240,243..244,247..249,252,280,284,336..337,
                     341,345,361,364..365,368..369,372)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340877"
ORIGIN      
        1 mtmprlassr wwyimpivfv tyslayldra nygfaaasgm addlritpgl ssllgalffl
       61 gyfffqvpga iyaekrsvkk lifvslilwg glatltgmva nvylligirf llgvveaavm
      121 pamlvylchw ftraersran tflilgnpvt ilwmsvvsgy lvehfswrwm fiieglpavi
      181 wafiwwrlvd drprqaawls gsekrdleda laaeqqgikp vknyreafrs pkvivlslqy
      241 fcwsigvygf vlwlpsilkh ganidiieag wlsalpylaa viamlgvswa sdrlqkrkrf
      301 vwpplliasi afygsyalgs ehfwlsyall vlagacmyap ygpffaivpe vlpanvagga
      361 malinsmgal gsfsgswlvg ylngitggpg asylfmsgal llsvlltvfl nphadkrepd
      421 aarahasrra apahp