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MULTISPECIES: transcriptional regulator PtxS [Pseudomonas].


LOCUS       WP_003113738             340 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003113738
VERSION     WP_003113738.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 340)
  AUTHORS   Daddaoua,A., Fillet,S., Fernandez,M., Udaondo,Z., Krell,T. and
            Ramos,J.L.
  TITLE     Genes for carbon metabolism and the ToxA virulence factor in
            Pseudomonas aeruginosa are regulated through molecular interactions
            of PtxR and PtxS
  JOURNAL   PLoS One 7 (7), e39390 (2012)
   PUBMED   22844393
REFERENCE   2  (residues 1 to 340)
  AUTHORS   Daddaoua,A., Krell,T., Alfonso,C., Morel,B. and Ramos,J.L.
  TITLE     Compartmentalized glucose metabolism in Pseudomonas putida is
            controlled by the PtxS repressor
  JOURNAL   J Bacteriol 192 (17), 4357-4366 (2010)
   PUBMED   20581202
REFERENCE   3  (residues 1 to 340)
  AUTHORS   Westfall,L.W., Luna,A.M., Francisco,M.S., Diggle,S.P.,
            Worrall,K.E., Williams,P., Camara,M. and Hamood,A.N.
  TITLE     The Pseudomonas aeruginosa global regulator MvaT specifically binds
            to the ptxS upstream region and enhances ptxS expression
  JOURNAL   Microbiology (Reading) 150 (Pt 11), 3797-3806 (2004)
   PUBMED   15528665
REFERENCE   4  (residues 1 to 340)
  AUTHORS   Colmer,J.A. and Hamood,A.N.
  TITLE     Characterization of ptxS, a Pseudomonas aeruginosa gene which
            interferes with the effect of the exotoxin A positive regulatory
            gene, ptxR
  JOURNAL   Mol Gen Genet 258 (3), 250-259 (1998)
   PUBMED   9645431
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR013246
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..340
                     /gene="ptxS"
     Protein         1..340
                     /product="transcriptional regulator PtxS"
                     /calculated_mol_wt=37260
     Region          12..82
                     /region_name="HTH_LACI"
                     /note="helix_turn _helix lactose operon repressor;
                     smart00354"
                     /db_xref="CDD:197675"
     Site            order(23..27,29..30,33,38,40,43,56,59,62..63,65..66)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     Site            56..65
                     /site_type="active"
                     /note="domain linker motif [active]"
                     /db_xref="CDD:143331"
     Region          72..333
                     /region_name="PBP1_RegR_EndR_KdgR-like"
                     /note="ligand-binding domain of DNA transcription
                     repressor RegR and other putative regulators such as KdgR
                     and EndR; cd06283"
                     /db_xref="CDD:380506"
     Site            order(72,79,86..87,89..90,93,102..107,118,121,125,258,
                     261..262,265)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:380506"
     Site            order(84..85,88,133,155,168,205,226,280,297)
                     /site_type="other"
                     /note="putative ligand binding site [chemical binding]"
                     /db_xref="CDD:380506"
ORIGIN      
        1 mngsvlpsrg rvtinqvaea agvskasvsr yiggdrqlla datarriera idqldyrpnq
       61 marglkrgrt rligmlvadi lnpysvavmh gvetacrehg yslvvcntdr ddeqerhhla
      121 alqsynvegl ivntlghhpg elralhrelp mvlvdrqlae ldtdlvgldn adaveqaldh
      181 lqhrgfrdil lvtepldgts sriervqafn asigrrpalk gqvlqtddff rdglraflsa
      241 sgpgpkalft cngvatlcat rqlrdlgcrl fdevgllald eldwyplvgs gitalaqptd
      301 eigrtaferl larlegdrep arrvtfpaql ivrgsthprg