MULTISPECIES: L-lyxonate dehydratase [Pseudomonas].

LOCUS       WP_003113703             391 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003113703
VERSION     WP_003113703.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 391)
  AUTHORS   Ghasempur,S., Eswaramoorthy,S., Hillerich,B.S., Seidel,R.D.,
            Swaminathan,S., Almo,S.C. and Gerlt,J.A.
  TITLE     Discovery of a novel L-lyxonate degradation pathway in Pseudomonas
            aeruginosa PAO1
  JOURNAL   Biochemistry 53 (20), 3357-3366 (2014)
   PUBMED   24831290
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR007606
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..391
                     /product="L-lyxonate dehydratase"
                     /calculated_mol_wt=44071
     Region          44..380
                     /region_name="MR_like_2"
                     /note="Mandelate racemase (MR)-like subfamily of the
                     enolase superfamily, subgroup 2. Enzymes of this subgroup
                     share three conserved carboxylate ligands for the
                     essential divalent metal ion (usually Mg2+), two
                     aspartates and a glutamate, and conserved catalytic...;
                     cd03327"
                     /db_xref="CDD:239443"
     Site            order(149,178,180,215,239,241,267,290,317,337)
                     /site_type="active"
                     /note="putative active site pocket [active]"
                     /db_xref="CDD:239443"
     Site            order(215,241,267)
                     /site_type="other"
                     /note="putative metal binding site [ion binding]"
                     /db_xref="CDD:239443"
ORIGIN      
        1 mkiksvrtrv fewkgkvvpp qahfctnasd ilfekgdamg sfrfhgwlvv eietddglvg
       61 igncalaprv akeivdlyla picigedpfd neyiwqkmyr rthawgrkgi gmaaisavdl
      121 aiwdimgkav nkpvfkllgg rtkekiwtya sklyandnld afleeaqgyl nqgftalkmr
      181 fgygpkdgpt gmrrnieqvr alrelagpdi dimlecymgw tleyarrmlp klaefeprwl
      241 eepviaddie gyvelkkmgi mpisggehef tghgfkdlle rravdviqyd tnrvggitaa
      301 rkinamaeaw svpviphagq lhnyhltmas taspmaeffp vfdvevgnel fyyvfkgepq
      361 pvdgyiqldd hkpglgleis eehlkdfiii e